Identification of Missing Proteins in Human Olfactory Epithelial Tissue by Liquid Chromatography-Tandem Mass Spectrometry
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwang, Heeyoun | - |
dc.contributor.author | Jeong, Ji Eun | - |
dc.contributor.author | Lee, Hyun Kyoung | - |
dc.contributor.author | Yun, Ki Na | - |
dc.contributor.author | An, Hyun Joo | - |
dc.contributor.author | Lee, Bonghee | - |
dc.contributor.author | Paik, Young-Ki | - |
dc.contributor.author | Jeong, Tae Seok | - |
dc.contributor.author | Yee, Gi Taek | - |
dc.contributor.author | Kim, Jin Young | - |
dc.contributor.author | Yoo, Jong Shin | - |
dc.date.available | 2020-02-27T08:41:20Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-12 | - |
dc.identifier.issn | 1535-3893 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3004 | - |
dc.description.abstract | We performed proteomic analyses of human olfactory epithelial tissue to identify missing proteins using liquid chromatography-tandem mass spectrometry. Using a next-generation proteomic pipeline with a < 1.0% false discovery rate at the peptide and protein levels, we identified 3731 proteins, among which five were missing proteins (POC7M7, P46721, P59826, Q658L1, and Q8N434). We validated the identified missing proteins using the corresponding synthetic peptides. No olfactory receptor (OR) proteins were detected in olfactory tissue, suggesting that detection of ORs would be very difficult. We also identified 49 and 50 alternative splicing variants mapped at the neXtProt and GENCODE databases, respectively, and 2000 additional single amino acid variants. This data set is available at the ProteomeXchange consortium via PRIDE repository (PXD010025). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | JOURNAL OF PROTEOME RESEARCH | - |
dc.title | Identification of Missing Proteins in Human Olfactory Epithelial Tissue by Liquid Chromatography-Tandem Mass Spectrometry | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000452930000028 | - |
dc.identifier.doi | 10.1021/acs.jproteome.8b00408 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PROTEOME RESEARCH, v.17, no.12, pp.4320 - 4324 | - |
dc.identifier.scopusid | 2-s2.0-85052289348 | - |
dc.citation.endPage | 4324 | - |
dc.citation.startPage | 4320 | - |
dc.citation.title | JOURNAL OF PROTEOME RESEARCH | - |
dc.citation.volume | 17 | - |
dc.citation.number | 12 | - |
dc.contributor.affiliatedAuthor | Lee, Bonghee | - |
dc.contributor.affiliatedAuthor | Jeong, Tae Seok | - |
dc.contributor.affiliatedAuthor | Yee, Gi Taek | - |
dc.type.docType | Article | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.