Size-Specific Dose Estimation In the Korean Lung Cancer Screening Project: Does a 32-cm Diameter Phantom Represent a Standard-Sized Patient n Korean Population
- Authors
- Kim, Eun Young; Kim, Tae Jung; Goo, Jin Mo; Kim, Hyae Young; Lee, Ji Won; Lee, Soojung; Lim, Jun-tae; Kim, Yeol
- Issue Date
- Nov-2018
- Publisher
- KOREAN RADIOLOGICAL SOC
- Keywords
- Low-dose CT; Radiation dose; Radiation dosage; Early detection
- Citation
- KOREAN JOURNAL OF RADIOLOGY, v.19, no.6, pp.1179 - 1186
- Journal Title
- KOREAN JOURNAL OF RADIOLOGY
- Volume
- 19
- Number
- 6
- Start Page
- 1179
- End Page
- 1186
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3140
- DOI
- 10.3348/kjr.2018.19.6.1179
- ISSN
- 1229-6929
- Abstract
- Objective: The purposes of this study were to evaluate size-specific dose estimate (SSDE) of low-dose CT (LDCT) in the Korean Lung Cancer Screening (K-LUCAS) project and to determine whether CT protocols from Western countries are appropriate for lung cancer screening in Korea. Materials and Methods: For participants (n = 256, four institutions) of K-LUCAS pilot study, volume CT dose index (CTDIvol) using a 32-cm diameter reference phantom was compared with SSDE, which was recalculated from CTDIvol using size-dependent conversion factor (f-size) based on the body size, as described in the American Association of Physicists in Medicine Report 204. This comparison was subsequently assessed by body mass index (BMI) levels (underweight/normal vs. overweight/obese), and automatic exposure control (AEC) adaptation (yes/no). Results: Size-specific dose estimate was higher than CTDIvol (2.22 +/- 0.75 mGy vs. 1.67 +/- 0.60 mGy, p < 0.001), since the f-size was larger than 1.0 for all participants. The ratio of SSDE to CTDIvol was higher in lower BMI groups; 1.26, 1.37, 1.43, and 1.53 in the obese (n = 103), overweight (n = 70), normal (n = 75), and underweight (n = 4), respectively. The ratio of SSDE to CTDIvol was greater in standard-sized participants than in large-sized participants independent of AEC adaptation; with AEC, SSDE/CTDIvol in large- vs. standard-sized participants: 1.30 +/- 0.08 vs. 1.44 +/- 0.08 (p < 0.001) and without AEC, 1.32 +/- 0.08 vs. 1.42 +/- 0.06 (p < 0.001). Conclusion: Volume CT dose index based on a reference phantom underestimates radiation exposure of LDCT in standardsized Korean participants. The optimal radiation dose limit needs to be verified for standard-sized Korean participants.
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