Dual Applicability of Polyaniline Coated Gold Nanorods: A Study of Antibacterial and Redox Activity
- Authors
- Liang, Xiaohong; Govindaraju, Saravanan; Yun, Kyusik
- Issue Date
- Jun-2018
- Publisher
- KOREAN BIOCHIP SOCIETY-KBCS
- Keywords
- Gold nanorods; Polyaniline; Electrochemical performance; Antibacterial properties
- Citation
- BIOCHIP JOURNAL, v.12, no.2, pp.137 - 145
- Journal Title
- BIOCHIP JOURNAL
- Volume
- 12
- Number
- 2
- Start Page
- 137
- End Page
- 145
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3745
- DOI
- 10.1007/s13206-017-2206-8
- ISSN
- 1976-0280
- Abstract
- Non-agglomerated, dual-purpose monodispersed gold nanorods (GNRs) were synthesized by using a seed-mediated method, and subsequent in situ chemical polymerization yielded polyaniline-coated gold nanorods (PANI-GNRs). The synthesized GNRs and PANI-GNRs were characterized by electron microscopic analyses, selected-area electron diffraction patterns, and element analyses. The prepared nanomaterials had an average length of 40 +/- 0.4 nm and a diameter of 15 +/- 0.2 nm. Furthermore, the PANI coating around the GNRs had a thickness of similar to 21 nm. These nanomaterials were also characterized by ultraviolet-visible and Fourier transform-infrared spectroscopies. While the absorption peaks of GNRs were observed at 520 and 675 nm, those of PANI-GNRs showed absorption maxima at 325 and 665 nm. The combination of 0.91 vol% of aniline with 5 mL of GNRs provided better electrochemical properties at 0.52 V and 1.30 V. The minimum inhibitory concentrations of laser-irradiated PANI-GNRs, PANI-GNRs, and laser-irradiated GNRs against Escherichia coli and Staphylococcus aureus were determined by using the micro-dilution method and compared to those of kanamycin (standard drug), revealing the significant bactericidal activity of laser-irradiated PANI-GNRs. This activity of the PANI-GNRs was also supported by the results of fluorescence and atomic force microscopy imaging. Thus, the synthesized nanomaterials can be potentially utilized for waste water treatment and biomedical/pharmaceutical applications.
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Collections - 바이오나노대학 > 바이오나노학과 > 1. Journal Articles
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