Assessing Vascular Changes Associated with Healthy Aging using 7T Magnetic Resonance Angiography
- Authors
- Jang, So-Ra; Park, Chan-A; Lee, Kyung-Jin; Lee, Yeong-Bae; Kim, Hang-Keun; Kang, Chang-Ki
- Issue Date
- Mar-2018
- Publisher
- KOREAN MAGNETICS SOC
- Keywords
- 7T MRI; MRA; lenticulostriate artery; vascular aging; vessel curvature
- Citation
- JOURNAL OF MAGNETICS, v.23, no.1, pp.61 - 67
- Journal Title
- JOURNAL OF MAGNETICS
- Volume
- 23
- Number
- 1
- Start Page
- 61
- End Page
- 67
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4024
- DOI
- 10.4283/JMAG.2018.23.1.061
- ISSN
- 1226-1750
- Abstract
- Aging is known to produce changes in the cerebral vasculature and circulation. We aimed to quantitatively assess age-related changes in the morphology of small perforating vessels, lenticulostriate arteries (LSAs). LSA images were acquired using ultra-high field 7-Tesla magnetic resonance imaging (7T MRI) from 24 young healthy volunteers (young group: YG) and 25 old healthy volunteers (old group: OG). Vessel-related factors such as curvature and tortuosity were analyzed using two-dimensional images. Our quantitative results demonstrated a fewer in their branches and a significantly more pronounced curvature in the OG compared to the YG These findings were further confirmed qualitatively using image analysis. Our study findings show that MR angiography utilizing ultra-high field MRI can provide high-resolution images that can identify morphological characteristics of small perforating vessels. Based on these features, it is possible to document age induced changes in cerebral small vessels.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 보건과학대학 > 방사선학과 > 1. Journal Articles
- 보건과학대학 > 의용생체공학과 > 1. Journal Articles
- 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4024)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.