Tumor Boost Using External Beam Radiation in Cervical Cancer Patients Unable to Receive Intracavitary Brachytherapy Outcome From a Multicenter Retrospective Study (Korean Radiation Oncology Group 1419)
DC Field | Value | Language |
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dc.contributor.author | Kim, Haeyoung | - |
dc.contributor.author | Kim, Young Seok | - |
dc.contributor.author | Joo, Ji Hyeon | - |
dc.contributor.author | Eom, Keun-Yong | - |
dc.contributor.author | Park, Won | - |
dc.contributor.author | Kim, Jin Hee | - |
dc.contributor.author | Lee, Jong Hoon | - |
dc.contributor.author | Kim, Yeon Sil | - |
dc.contributor.author | Lee, Seok Ho | - |
dc.contributor.author | Ahn, Kijung | - |
dc.contributor.author | Kim, Yong Bae | - |
dc.contributor.author | Lee, Me-Yeon | - |
dc.contributor.author | Chang, Sei Kyung | - |
dc.date.available | 2020-02-27T12:40:55Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1048-891X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4129 | - |
dc.description.abstract | Purpose: We conducted this study to evaluate the outcomes of external-beam radiotherapy tumor boost (EBRT-B) in cervical cancer patients who could not receive intracavitary brachytherapy. Methods: A total of 11 hospitals provided the data of patients who received EBRT-B during the period from January 2005 through October 2012. Results: A total of 75 patients were included. The median radiotherapy dose was 46 Gy (range, 40-54 Gy) for whole pelvis and 24 Gy (range, 9-35 Gy) for EBRT-B. Initial tumor responses assessed at 2 to 6 months after radiotherapy were as follows: 46 with complete response, 22with partial response, 2with stable disease, and 3with progressive disease. After a median follow-up time of 33 months, 30 patients (40.0%) showed disease progression including 21 (28.0%) with local progression. The 5-year local failure-free survival rate was 70.0%. Achieving complete response at the first follow-up visit and an overall treatment timeof 53 days or less were significantly related to favorable local failure-free survival. The rate of grade 3 or higher toxicity was 2.6%. Conclusions: Approximately 70% of patients had local tumor control after curative radiotherapy using EBRT-B. Early tumor response and overall treatment time of 53 days or lesswere closely associated with favorable local control. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | - |
dc.subject | UTERINE CERVIX | - |
dc.subject | THERAPY | - |
dc.subject | RADIOTHERAPY | - |
dc.subject | CARCINOMA | - |
dc.title | Tumor Boost Using External Beam Radiation in Cervical Cancer Patients Unable to Receive Intracavitary Brachytherapy Outcome From a Multicenter Retrospective Study (Korean Radiation Oncology Group 1419) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000424045900024 | - |
dc.identifier.doi | 10.1097/IGC.0000000000001155 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, v.28, no.2, pp.371 - 378 | - |
dc.identifier.scopusid | 2-s2.0-85041453596 | - |
dc.citation.endPage | 378 | - |
dc.citation.startPage | 371 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | - |
dc.citation.volume | 28 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Lee, Seok Ho | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Brachytherapy | - |
dc.subject.keywordAuthor | Radiotherapy | - |
dc.subject.keywordAuthor | Uterine cervical neoplasm | - |
dc.subject.keywordPlus | UTERINE CERVIX | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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