항혈소판제와 비스테로이드성소염진통제의 동시 투약으로 인한 출혈 사례Bleeding after Taking Dual Antiplatelets and NSAID Concurrently
- Other Titles
- Bleeding after Taking Dual Antiplatelets and NSAID Concurrently
- Authors
- 서정민; 최중혁; 손병우; 이승민; 채현우; 강근형; 지은희
- Issue Date
- 2018
- Publisher
- 한국임상약학회
- Keywords
- Bleeding; antiplatelet agents; NSAIDs; stenting; osteoarthritis
- Citation
- 한국임상약학회지, v.28, no.3, pp.250 - 253
- Journal Title
- 한국임상약학회지
- Volume
- 28
- Number
- 3
- Start Page
- 250
- End Page
- 253
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4719
- DOI
- 10.24304/kjcp.2018.28.3.167
- ISSN
- 1226-6051
- Abstract
- When stenting is applied to treat myocardial infarction, antiplatelet agents are administered to prevent thrombosis, which increases
the risk of bleeding. Patients with myocardial infarction are also more likely to have osteoarthritis simultaneously, because both
diseases occur frequently in elderly patients. Patients with osteoarthritis often use analgesics, especially nonsteroidal antiinflammatory
drugs (NSAIDs); hence, patients with both diseases use analgesics and antiplatelet agents simultaneously. The risk of
bleeding increases with the use of antiplatelet agents and this is further increased when NSAIDs are added. We would like to report
a case that reflects this situation. A 60-year-old man underwent stenting after ST-elevation myocardial infarction, and was treated
with aspirin and clopidogrel. This patient also received a pelubiprofen prescription from another physician to treat osteoarthritis.
After the patient took pelubiprofen twice, he found a bruise on his wrist and reported it to the pharmacist. It is unlikely that this is
rare in community pharmacies, so pharmacists should pay careful attention to the concomitant administration of analgesics to
patients receiving antiplatelet agents and should provide appropriate education to patients.
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