Levosulpiride 복용 이후 발생한 고프로락틴혈증 및 그 인과성 분석: 지역약국에서 보고된 부작용 증례Hyperprolactinemia after taking Levosulpiride and its Causality Assessment: An Adverse Event Reported by a Community Pharmacy
- Other Titles
- Hyperprolactinemia after taking Levosulpiride and its Causality Assessment: An Adverse Event Reported by a Community Pharmacy
- Authors
- 이희영; 조유진; 윤중식; 지은희
- Issue Date
- Jun-2018
- Publisher
- 한국임상약학회
- Keywords
- Levosulpiride; adverse drug reaction; hyperprolactinemia; causality assessment; community pharmacy
- Citation
- 한국임상약학회지, v.28, no.2, pp.154 - 157
- Journal Title
- 한국임상약학회지
- Volume
- 28
- Number
- 2
- Start Page
- 154
- End Page
- 157
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4983
- DOI
- 10.24304/kjcp.2018.28.2.154
- ISSN
- 1226-6051
- Abstract
- Levosulpiride is one of the most frequently prescribed medicines in Korea. An adverse drug reaction (ADR) after takinglevosulpiride was reported at a community pharmacy in Korea. A 31-year-old woman reported the symptoms of lactation andamenorrhea after taking levosulpiride; an evaluation of whether these symptoms were caused by the medication was thereforenecessary. Several tools can be used to determine if the ADR resulted from the administered drug or other factors, including theWorld Health Organization-Uppsala Monitoring Centre (WHO-UMC) criteria, the Naranjo scale, and the Korean causality assessmentalgorithm (Ver. 2). The causality was evaluated as “possible” by the WHO-UMC and Naranjo scales, but as “probable” by theKorean causality assessment algorithm (Ver. 2). In conclusion, the information provided did not indicate definite causality and therewere slight differences in the results obtained from each assessment method.
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