Stem Cell Therapy for Neurogenic Bladder After Spinal Cord Injury: Clinically Possible?Stem Cell Therapy for Neurogenic Bladder After Spinal Cord Injury: Clinically Possible?
- Other Titles
- Stem Cell Therapy for Neurogenic Bladder After Spinal Cord Injury: Clinically Possible?
- Authors
- 김수진; 조영삼; 박종목; 나영길; 김계환
- Issue Date
- May-2020
- Publisher
- 대한배뇨장애요실금학회
- Keywords
- Urinary bladder; Neurogenic; Spinal cord injury; Stem cells; Clinical trials
- Citation
- International Neurourology Journal, v.24, pp.S3 - 10
- Journal Title
- International Neurourology Journal
- Volume
- 24
- Start Page
- S3
- End Page
- 10
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/50877
- DOI
- 10.5213/inj.2040150.075
- ISSN
- 2093-4777
- Abstract
- Neurogenic bladder (NB) after spinal cord injury (SCI) is a common complication that inhibits normal daily activities and reduces the quality of life. Regrettably, the current therapeutic methods for NB are inadequate. Therefore, numerous studies have been conducted to develop new treatments for NB associated with SCI. Moreover, a myriad of preclinical and clinical trials on the effects and safety of stem cell therapy in patients with SCI have been performed, and several studies have demonstrated improvements in urodynamic parameters, as well as in sensory and motor function, after stem cell therapy. These results are promising; however, further high-quality clinical studies are necessary to compensate for a lack of randomized trials, the modest number of participants, variation in the types of stem cells used, and inconsistency in routes of administration.
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