Applications of chitosan nanoparticles to enhance absorption and bioavailability of tea polyphenols: A review
- Authors
- Liang, Jin; Yan, Hua; Puligundla, Pradeep; Gao, Xueling; Zhou, Yibin; Wan, Xiaochun
- Issue Date
- Aug-2017
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Chitosan; Nanoparticles; Delivery system; Tea polyphenols; Absorption; Bioavailability
- Citation
- FOOD HYDROCOLLOIDS, v.69, pp.286 - 292
- Journal Title
- FOOD HYDROCOLLOIDS
- Volume
- 69
- Start Page
- 286
- End Page
- 292
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5883
- DOI
- 10.1016/j.foodhyd.2017.01.041
- ISSN
- 0268-005X
- Abstract
- Tea polyphenols find a wide range of applications in food, medical and pharmaceutical fields owing to their multi-health benefits including antioxidant and antibacterial activities, cancer prevention, antiradiation and immune enhancement. However, the low absorption rate of tea polyphenols impedes their bioactivity in vivo. The low absorption and bioavailability have been attributed to their poor stability, passive diffusion, and active efflux in the gastrointestinal (GI) tract. Nanoparticle delivery system based on chitosan (CS), a natural biomaterial, has been widely applied in pharmaceutical field to enhance absorption of bioactive compounds. A few studies reported the enhanced absorption and bioavailability of tea polyphenols by the application of chitosan nanoparticles. This review describes the fabrication methods and potential benefits of chitosan nanoparticles as delivery systems for tea polyphenols for their enhanced absorption in the GI tract. In addition, challenges and future trends of chitosan nanoparticles as a carrier for oral delivery of tea polyphenols are also discussed. (C) 2017 Elsevier Ltd. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 바이오나노대학 > 식품생물공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5883)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.