Association of serum vitamin D with osteosarcopenic obesity: Korea National Health and Nutrition Examination Survey 2008-2010
DC Field | Value | Language |
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dc.contributor.author | Kim, Jinhee | - |
dc.contributor.author | Lee, Yunhwan | - |
dc.contributor.author | Kye, Seunghee | - |
dc.contributor.author | Chung, Yoon-Sok | - |
dc.contributor.author | Lee, Okhee | - |
dc.date.available | 2020-02-27T19:41:20Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 2190-5991 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6248 | - |
dc.description.abstract | Background Serum vitamin D levels have been reported to be associated with individual components of body composition. However, the relationship between serum vitamin D and combined indices of adverse body composition is largely unknown. This cross-sectional study examined the association between serum vitamin D and osteosarcopenic obesity in a nationally representative sample of middle-aged and older adults. Methods We analysed the Korea National Health and Nutrition Examination Surveys (IV and V) conducted in 2008-2010, consisting of 5908 (2485 men, 3423 women) aged 50years. Serum vitamin D levels were determined by radioimmunoassay, and body composition was evaluated by dual-energy x-ray absorptiometry. The association between serum vitamin D levels and the number of abnormalities in body composition, including osteosarcopenic obesity, a low bone and muscle mass with concurrent high fat mass, was analysed by multinomial logistic regression adjusting for covariates. Results In men, after controlling for covariates, higher vitamin D levels were associated with a significantly reduced likelihood of the number of phenotypes of adverse body composition (P for trend<0.05). Those in the highest tertile group of serum vitamin D levels, compared with those in the lowest tertile, were less likely to have adverse body composition, numbering one (odds ratio [OR]=0.67, 95% confidence interval [CI]: 0.49, 0.92), two (OR=0.49, 95% CI: 0.33, 0.73), and three (osteosarcopenic obesity; OR=0.42, 95% CI: 0.26, 0.67). In women, those in the highest tertile group of serum vitamin D levels, compared with those in the lowest tertile, were less likely to have osteosarcopenic obesity (OR=0.55, 95% CI: 0.33, 0.93). Vitamin D deficiency (<20ng/mL) in men was significantly associated with an increased likelihood of a higher number of adverse body composition, especially for osteosarcopenic obesity (OR=2.08, 95% CI: 1.42, 3.03). Vitamin D deficient women, compared with those having normal levels of serum vitamin D, were also more likely to demonstrate osteosarcopenic obesity (OR=1.99, 95% CI: 1.30, 3.05). Conclusions A high serum vitamin D level in mid- and late-life was associated with reduced odds of multiple adverse body composition, especially osteosarcopenic obesity, suggesting potential health benefits of maintaining adequate levels of vitamin D. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE | - |
dc.subject | SKELETAL-MUSCLE MASS | - |
dc.subject | BODY-FAT | - |
dc.subject | FRACTURE RISK | - |
dc.subject | BONE HEALTH | - |
dc.subject | D-RECEPTOR | - |
dc.subject | OLDER MEN | - |
dc.subject | SARCOPENIA | - |
dc.subject | OSTEOPOROSIS | - |
dc.subject | DEFICIENCY | - |
dc.subject | SEX | - |
dc.title | Association of serum vitamin D with osteosarcopenic obesity: Korea National Health and Nutrition Examination Survey 2008-2010 | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000398693100009 | - |
dc.identifier.doi | 10.1002/jcsm.12154 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, v.8, no.2, pp.259 - 266 | - |
dc.identifier.scopusid | 2-s2.0-84990852895 | - |
dc.citation.endPage | 266 | - |
dc.citation.startPage | 259 | - |
dc.citation.title | JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Kye, Seunghee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Vitamin D | - |
dc.subject.keywordAuthor | Osteosarcopenic obesity | - |
dc.subject.keywordAuthor | Osteoporosis | - |
dc.subject.keywordAuthor | Sarcopenia | - |
dc.subject.keywordAuthor | Obesity | - |
dc.subject.keywordPlus | SKELETAL-MUSCLE MASS | - |
dc.subject.keywordPlus | BODY-FAT | - |
dc.subject.keywordPlus | FRACTURE RISK | - |
dc.subject.keywordPlus | BONE HEALTH | - |
dc.subject.keywordPlus | D-RECEPTOR | - |
dc.subject.keywordPlus | OLDER MEN | - |
dc.subject.keywordPlus | SARCOPENIA | - |
dc.subject.keywordPlus | OSTEOPOROSIS | - |
dc.subject.keywordPlus | DEFICIENCY | - |
dc.subject.keywordPlus | SEX | - |
dc.relation.journalResearchArea | Geriatrics & Gerontology | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Geriatrics & Gerontology | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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