Anti-Neurodegenerative Biflavonoid Glycosides from Impatiens balsamina
DC Field | Value | Language |
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dc.contributor.author | Kim, Chung Sub | - |
dc.contributor.author | Bae, Munhyung | - |
dc.contributor.author | Oh, Joonseok | - |
dc.contributor.author | Subedi, Lalita | - |
dc.contributor.author | Suh, Won Se | - |
dc.contributor.author | Choi, Sang Zin | - |
dc.contributor.author | Son, Mi Won | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Choi, Sang Un | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.contributor.author | Lee, Kang Ro | - |
dc.date.available | 2020-02-27T19:43:49Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017-02 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6415 | - |
dc.description.abstract | Four biflavonoid glycosides, balsamisides A-D (1-4), and nine known compounds (5-13) were obtained from the white petals of Impatiens balsamina. The 2D structures of the purified phytochemicals were established using conventional NMR techniques in addition to the new long-range HSQMBC NMR experiment. Acid hydrolysis followed by experimental and quantum-mechanics-based ECD data analysis permitted full configurational assignment of the purified metabolites. Compounds 1-13 were assessed for their potential to impede the generation of nitric oxide in lipopolysaccharide-stimulated BV2 cells. They were also investigated for potential neuroprotective activity using C6 cells and cytotoxicity against some human tumor cell lines, but were inactive (IC50 > 10 mu M) against all the cell lines. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | JOURNAL OF NATURAL PRODUCTS | - |
dc.title | Anti-Neurodegenerative Biflavonoid Glycosides from Impatiens balsamina | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000395046900028 | - |
dc.identifier.doi | 10.1021/acs.jnatprod.6b00981 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.80, no.2, pp.471 - 478 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85013787067 | - |
dc.citation.endPage | 478 | - |
dc.citation.startPage | 471 | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 80 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Bae, Munhyung | - |
dc.contributor.affiliatedAuthor | Subedi, Lalita | - |
dc.contributor.affiliatedAuthor | Kim, Sun Yeou | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | FLAVONOID GLYCOSIDES | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | PETALS | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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