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Effects of beryllium on human serum immunoglobulin and lymphocyte subpopulation
- Authors
- Kim K.-W.; Kim D.; Won Y.L.; Kang S.-K.
- Issue Date
- Jun-2013
- Publisher
- 한국독성학회
- Keywords
- Beryllium; Immunoglobulins; Short-term exposure; T lymphocyte subpopulation
- Citation
- Toxicological Research, v.29, no.2, pp.115 - 120
- Journal Title
- Toxicological Research
- Volume
- 29
- Number
- 2
- Start Page
- 115
- End Page
- 120
- ISSN
- 1976-8257
- Abstract
- To investigate the effects of short-term exposure of beryllium on the human immune system, the proportion of T-lymphocytes such as CD3+, CD4+, CD8+, CD95, and NK cells, andthe proportion of B cells and TNFα level in peripheral blood and immunoglobulins in the serum of 43 exposed workers and 34 healthy control subjects were studied. External exposure to beryllium was measured by atomic absorption spectrometer as recommended by the NIOSH analytical method 7300. T lymphocyte subpopulation analysis was carried out with flow cytometer. The working duration of exposed workers was less than 3 months and the mean ambient beryllium level was 3.4 μg/m
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Related Researcher
- Kang, Seong Kyu
- College of Medicine (Department of Medicine)