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Diagnosis and treatment of growth hormone deficiency: A position statement from Korean endocrine society and Korean society of pediatric endocrinology

Authors
Kim, J.H.Chae, H.W.Chin, S.O.Ku, C.R.Park, K.H.Lim, D.J.Kim, K.J.Lim, J.S.Kim, G.Choi, Y.M.Ahn, S.H.Jeon, M.J.Hwangbo, Y.Lee, J.H.Kim, B.K.Choi, Y.J.Lee, K.A.Moon, S.-S.Ahn, H.Y.Choi, H.S.Hong, S.M.Shin, D.Y.Seo, J.A.Kim, S.H.Oh, S.Yu, S.H.Kim, B.J.Shin, C.H.Kim, S.-W.Kim, C.H.Lee, E.J.
Issue Date
Jun-2020
Publisher
Korean Endocrine Society
Keywords
Dwarfism; Growth hormone; Hormone replacement therapy; Hypopituitarism; Pituitary
Citation
Endocrinology and Metabolism, v.35, no.2, pp.272 - 287
Journal Title
Endocrinology and Metabolism
Volume
35
Number
2
Start Page
272
End Page
287
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/79391
DOI
10.3803/EnM.2020.35.2.272
ISSN
2093-596X
Abstract
Growth hormone (GH) deficiency is caused by congenital or acquired causes and occurs in childhood or adulthood. GH replacement therapy brings benefits to body composition, exercise capacity, skeletal health, cardiovascular outcomes, and quality of life. Before initiating GH replacement, GH deficiency should be confirmed through proper stimulation tests, and in cases with proven genetic causes or structural lesions, repeated GH stimulation testing is not necessary. The dosing regimen of GH replacement therapy should be individualized, with the goal of minimizing side effects and maximizing clinical improvements. The Korean Endocrine Society and the Korean Society of Pediatric Endocrinology have developed a position statement on the diagnosis and treatment of GH deficiency. This position statement is based on a systematic review of evidence and expert opinions. © 2020 Korean Endocrine Society
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