Height is associated with dyslipidemia in korean premenopausal women: Data from the korea national health and nutrition examination survey
- Authors
- Hwang, In Cheol; Park, Young Min; Kang, Woong Chol; Moon, Jeonggeun
- Issue Date
- Nov-2020
- Publisher
- KARGER
- Citation
- CARDIOLOGY, v.145, no.11, pp.736 - 739
- Journal Title
- CARDIOLOGY
- Volume
- 145
- Number
- 11
- Start Page
- 736
- End Page
- 739
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/79752
- DOI
- 10.1159/000509631
- ISSN
- 0008-6312
- Abstract
- Background: The association between height and cardiovascular disease (CVD) has been reported in epidemiological studies for decades; however, the mechanism for this relationship is still unclear. We previously reported that dyslipidemia was associated with adult height in Korean men without CVD. Objectives: This study explored the potential-relationship between height and dyslipidemia in premenopausal women. Methods: This study used data from the 2007-2016 Korea National Health and Nutritional Examination Survey (KNHANES). We identified 16,361 premenopausal women aged ≥19 years without a history of CVD (myocardial infarction/stroke) or cancer. Fasting total cholesterol, triglyceride, and high-density lipoprotein cholesterol (HDL-C) levels were measured. Dyslipidemia was further classified as hypercholesterolemia (total cholesterol level ≥240 mg/dL or treatment with lipid-lowering medications), hypertriglyceridemia (triglyceride level ≥200 mg/dL), and low HDL-C (HDL-C level <40 mg/dL). Subjects were divided into four groups by their height (<155, 155-159.9, 160-164.9, and ≥165 cm), and the prevalence of dyslipidemia was compared. Results: Multiple regression analysis revealed that short premenopausal women had a higher likelihood of hypercholesterolemia (ptrend = 0.002), hypertriglyceridemia (ptrend = 0.010), and low HDL-C (ptrend = 0.002) when adjusted for age, comorbidities, waist circumference, health-related habits, and economic status. Conclusion: There was a dose-dependent correlation between adult height and adverse lipid profile in premenopausal Korean women who did not have CVD. This finding could serve as further evidence that dyslipidemia can be a link between shortness and CVD. © 2020 Lippincott Williams and Wilkins. All rights reserved.
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