Comparison of Outcomes after Device Closure with Transseptal Puncture and Standard Technique in Patients with Patent Foramen Ovale and Ischemic Events
- Authors
- Moon, Jeonggeun; Kang, Woong Chol; Kim, Sihoon; Kim, Myeong Gun; Oh, Pyung Chun; Park, Yae Min; Chung, Wook-Jin; Choi, Deok Young; Lee, Ji Yeon; Lee, Yeong-Bae; Hwang, Hee Young; Ahn, Taehoon
- Issue Date
- Aug-2016
- Publisher
- WILEY-BLACKWELL
- Citation
- JOURNAL OF INTERVENTIONAL CARDIOLOGY, v.29, no.4, pp.400 - 405
- Journal Title
- JOURNAL OF INTERVENTIONAL CARDIOLOGY
- Volume
- 29
- Number
- 4
- Start Page
- 400
- End Page
- 405
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8056
- DOI
- 10.1111/joic.12296
- ISSN
- 0896-4327
- Abstract
- Objectives: The purpose of this study was to compare the effectiveness of device closure with the transseptal puncture and standard technique in patients with patent foramen ovale (PFO) and ischemic events. Methods: Eighty-two consecutive patients (men: 60 patients, mean age: 45.2 years) who underwent PFO closure with the Amplatzer PFO Occluder were enrolled. PFO closure with the transseptal puncture was performed in 22 patients (transseptal puncture technique, group I). In the remaining patients (n = 60), PFO closure was performed with the standard technique (group II). The co-primary end points were the incidence of significant residual shunt on follow-up transesophageal echocardiography (TEE) and a composite of death, stroke, transient ischemic attack (TIA), and peripheral embolism. Results: Baseline characteristics were similar between the two groups. On TEE, despite similar grade of interatrial right-to-left shunt, shunt at rest/septal hypermobility was less common in group I than in group II (40.9% vs. 72.9%, P<0.010). The device was successfully implanted in all patients. On follow-up TEE, significant residual shunt was more common in group I than in group II (28.6% vs. 4.3%, P = 0.021). In addition, composite of death, stroke, TIA, or peripheral embolism was more common in group I than in group II (13.6% vs. 0%, P = 0.017) during the follow-up period (mean 25.4 months). Conclusion: Compared to the standard technique, PFO closure with the transseptal puncture technique showed higher incidence of residual shunt and ischemic events. Therefore, this technique might be considered in only highly selected patients as the last option.
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