Ag-Deposited Porous Silicon as a SERS-Active Substrate for the Sensitive Detection of Catecholamine Neurotransmitters
- Authors
- Vo, Van-The; Gwon, Youngju; Phung, Viet-Duc; Son, Young-Don; Kim, Jong-Hoon; Lee, Sang-Wha
- Issue Date
- May-2021
- Publisher
- KOREAN INST METALS MATERIALS
- Keywords
- Porous silicon; Ag-deposited; Dopamine; Norepinephrine; Surface-enhanced Raman scattering
- Citation
- ELECTRONIC MATERIALS LETTERS, v.17, no.3, pp.292 - 298
- Journal Title
- ELECTRONIC MATERIALS LETTERS
- Volume
- 17
- Number
- 3
- Start Page
- 292
- End Page
- 298
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80978
- DOI
- 10.1007/s13391-021-00281-0
- ISSN
- 1738-8090
- Abstract
- The sensitive detection of various neurotransmitters is very useful in diagnosing diseases related to the dysfunction of the neurotransmitter system. Surface-enhanced Raman scattering (SERS) is one of the best methods for bio-analyte detection as it provides a molecular fingerprint at a trace concentration level. In this study, Ag-deposited porous silicon (Ag@pSi) was fabricated as a SERS-active substrate via metal-assisted chemical etching and electroless plating methods. Dopamine (DA) and norepinephrine (NE) neurotransmitters were tested as probing analytes. The Ag@pSi substrate demonstrated the sensitive detection of the neurotransmitters (DA and NE) over the wide concentration range (from 10(-6) to 10(-)(10) M), with a good linearity between the intensity of specific Raman peak and the log-scale concentration. The Ag@pSi substrate also distinguished the individual analytes in a mixture of DA and NE at 10(-8) M, confirming the efficacy of the developed SERS substrate for the selective detection of neurotransmitters. [GRAPHICS] .
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 공과대학 > 화공생명공학과 > 1. Journal Articles
- 의과대학 > 의학과 > 1. Journal Articles
- 보건과학대학 > 의용생체공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80978)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.