An actively decoupled dual transceiver coil system for continuous ASL at 7 T
- Authors
- Stafford, Randall B.; Woo, Myung-Kyun; Oh, Se-Hong; Dolui, Sudipto; Zhao, Tiejun; Kim, Young-Bo; Detre, John A.; Cho, Zang-Hee; Lee, Jongho
- Issue Date
- Jun-2016
- Publisher
- WILEY-BLACKWELL
- Keywords
- magnetic resonance imaging; arterial spin labeling; 7 T; specific absorption rate; labeling coils; B-1-mapping; B-0-mapping
- Citation
- INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY, v.26, no.2, pp.106 - 115
- Journal Title
- INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY
- Volume
- 26
- Number
- 2
- Start Page
- 106
- End Page
- 115
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8209
- DOI
- 10.1002/ima.22165
- ISSN
- 0899-9457
- Abstract
- 7 T arterial spin labeling (ASL) faces major challenges including the increased specific absorption rate (SAR) and increased B-0 and B-1 inhomogeneity. This work describes the design and implementation of a dual-coil system that allows for continuous ASL (CASL) at 7 T. This system consisted of an actively detunable eight-channel transceiver head coil, and a three-channel transceiver labeling coil. Four experiments were performed in 5 healthy subjects: (i) to demonstrate that active detuning during ASL labeling reduces magnetization transfer; (ii) to measure the B-1 profile at the labeling plane; (iii) to quantify B-0 off-resonance at the labeling plane; and (iv) to collect in vivo CASL data. The magnetization transfer ratio in the head coil was reduced to 0.0 +/- 0.2% by active detuning during labeling. The measured B-1 profiles in all 5 subjects were sufficient to satisfy the flow-driven adiabatic inversion necessary for CASL, however the actual labeling efficiency was significantly impacted by B-0 off-resonance at the labeling plane. The measured CASL percent signal change in gray matter (0.94%+/- 0.10%) corresponds with the low labeling efficiency predicted by the B-0 off-resonance. This work demonstrates progress in the technical implementation of 7 T CASL, and reinforces the need for improved B-0 homogeneity at the labeling plane.
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