한의학 이론 연구를 위한 새로운 방법: 네트워크 약리학을 활용한 약물중심 접근법Novel Method to Investigating Korean Medicine Theory: Drug-centered Approach Employing Network Pharmacology
- Other Titles
- Novel Method to Investigating Korean Medicine Theory: Drug-centered Approach Employing Network Pharmacology
- Authors
- 이원융; 김창업; 이충열
- Issue Date
- Oct-2021
- Publisher
- 한의병리학회
- Keywords
- Korean medicine theory; Network pharmacology; Drug-centered approach
- Citation
- 동의생리병리학회지, v.35, no.5, pp.125 - 131
- Journal Title
- 동의생리병리학회지
- Volume
- 35
- Number
- 5
- Start Page
- 125
- End Page
- 131
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/82533
- ISSN
- 1738-7698
- Abstract
- The scientific understanding of Korean medicine theory remains largely unknown, since there is a lack of proper methods to investigate its complex and unique characteristics. Here, we introduce a drug-centered approach, a novel method to investigate Korean medicine theory by analyzing the mechanisms of herbal medicines. This method can be effectively conducted by employing network pharmacology that can analyze the systems-level mechanisms of herbal medicines on a large scale. Firstly, we introduce the method of network pharmacology that are applied to analyze the mechanisms of herbal medicines in a step-by-step manner. Then, we show how the drug-centered approach employing network pharmacology can be applied to investigate Korean medicine theory by describing studies that identify the biological correlates of the cold-hot nature of herbs, spleen qi deficiency syndrome, or Sasang constitution. Finally, we discuss the limitations and future directions of the proposed approach in two aspects: The methods of network pharmacology for a drug-centered approach and the process of inferring Korean medicine theory through it. We believe that a drug-centered approach employing network pharmacology will provide an advanced scientific understanding of Korean medicine theory and contribute to its development by generating biologically plausible hypothesis.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 한의과대학 > 한의예과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/82533)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.