A Tubular Biomaterial Construct Exhibiting a Negative Poisson's Ratio
DC Field | Value | Language |
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dc.contributor.author | Lee, Jin Woo | - |
dc.contributor.author | Soman, Pranav | - |
dc.contributor.author | Park, Jeong Hun | - |
dc.contributor.author | Chen, Shaochen | - |
dc.contributor.author | Cho, Dong-Woo | - |
dc.date.available | 2020-02-28T01:45:31Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-05-27 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8277 | - |
dc.description.abstract | Developing functional small-diameter vascular grafts is an important objective in tissue engineering research. In this study, we address the problem of compliance mismatch by designing and developing a 3D tubular construct that has a negative Poisson's ratio v(xy) (NPR). NPR constructs have the unique ability to expand transversely when pulled axially, thereby resulting in a highly-compliant tubular construct. In this work, we used projection stereolithography to 3D-print a planar NPR sheet composed of photosensitive poly(ethylene) glycol diacrylate biomaterial. We used a step-lithography exposure and a stitch process to scale up the projection printing process, and used the cut-missing rib unit design to develop a centimeter-scale NPR sheet, which was rolled up to form a tubular construct. The constructs had Poisson's ratios of -0.6 <= -v(xy) <= -0.1. The NPR construct also supports higher cellular adhesion than does the construct that has positive v(xy). Our NPR design offers a significant advance in the development of highly-compliant vascular grafts. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.subject | SMALL-INTESTINAL SUBMUCOSA | - |
dc.subject | VASCULAR GRAFTS | - |
dc.subject | BIODEGRADABLE POLYMER | - |
dc.subject | PULMONARY-ARTERY | - |
dc.subject | AUXETIC BEHAVIOR | - |
dc.subject | BLOOD-VESSEL | - |
dc.subject | HOLY-GRAIL | - |
dc.subject | IN-VITRO | - |
dc.subject | GROWTH | - |
dc.subject | MODEL | - |
dc.title | A Tubular Biomaterial Construct Exhibiting a Negative Poisson's Ratio | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000376883000005 | - |
dc.identifier.doi | 10.1371/journal.pone.0155681 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.11, no.5 | - |
dc.identifier.scopusid | 2-s2.0-84973124341 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 11 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Lee, Jin Woo | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SMALL-INTESTINAL SUBMUCOSA | - |
dc.subject.keywordPlus | VASCULAR GRAFTS | - |
dc.subject.keywordPlus | BIODEGRADABLE POLYMER | - |
dc.subject.keywordPlus | PULMONARY-ARTERY | - |
dc.subject.keywordPlus | AUXETIC BEHAVIOR | - |
dc.subject.keywordPlus | BLOOD-VESSEL | - |
dc.subject.keywordPlus | HOLY-GRAIL | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | MODEL | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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