Mohangic Acids A-E, p-Aminoacetophenonic Acids from a Marine-Mudflat-Derived Streptomyces sp.
- Authors
- Bae, Munhyung; Moon, Kyuho; Kim, Jihye; Park, Hyen Joo; Lee, Sang Kook; Shin, Jongheon; Oh, Dong-Chan
- Issue Date
- Feb-2016
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.332 - 339
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Volume
- 79
- Number
- 2
- Start Page
- 332
- End Page
- 339
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83311
- DOI
- 10.1021/acs.jnatprod.5b00956
- ISSN
- 0163-3864
- Abstract
- Mohangic acids A-E (1-5) were isolated from a marine Streptomyces sp. collected from a mudflat in Buan, Republic of Korea. Comprehensive spectroscopic analysis revealed that the mohangic acids are new members of the p-aminoacetophenonic acid class. The relative and absolute configurations of the mohangic acids were determined by J-based configuration analysis and by the application of bidentate chiral NMR solvents followed by C-13 NMR analysis, chemical derivatization, and circular dichroism spectroscopy. Mohangic acid E (5), which is the first glycosylated compound in the p-aminoacetophenonic acid family, displayed significant quinone reductase induction activity.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 약학대학 > 약학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83311)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.