Recent Advances in Allergen-Specific Immunotherapy in Humans: A Systematic Review
- Authors
- 이상표; 신유섭; 강성윤; 김태범; 이상민
- Issue Date
- Feb-2022
- Publisher
- 대한면역학회
- Keywords
- Allergy; Immunologic desensitization; Intradermal injection; Transcutaneous administration; Intralymphatic injection; Allergens
- Citation
- Immune Network, v.22, no.1, pp.1 - 13
- Journal Title
- Immune Network
- Volume
- 22
- Number
- 1
- Start Page
- 1
- End Page
- 13
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83813
- DOI
- 10.4110/in.2022.22.e12
- ISSN
- 1598-2629
- Abstract
- Allergen-specific immunotherapy (AIT) is presumed to modulate the natural course of allergic disease by inducing immune tolerance. However, conventional AITs, such as subcutaneous immunotherapy and sublingual immunotherapy, require long treatment durations and often provoke local or systemic hypersensitivity reactions. Therefore, only <5% of allergy patients receive AIT as second-line therapy. Novel administration routes, such as intralymphatic, intradermal and epicutaneous immunotherapies, and synthetic recombinant allergen preparations have been evaluated to overcome these limitations. We will review the updated views of diverse AIT methods, and discuss the limitations and opportunities of the AITs for the treatment of allergic diseases in humans.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83813)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.