Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
- Authors
- 윤신교; 김미소; 홍용상; 김한상; 김승태; 김지훈; 윤홍석; 유창훈; 안희경; 김효송; 이인희; 김인호; 박인근; 정재호; 천재경; 김진원; 윤지나; 임선민; 차용준; 장세진; 장대영; 김태원; 강진형; 김지현
- Issue Date
- Jan-2022
- Publisher
- 대한암학회
- Keywords
- Next-generation sequencing; Molecular tumor board; Advanced solid cancer; Precision medicine; Genomic alterations
- Citation
- Cancer Research and Treatment, v.54, no.1, pp.1 - 9
- Journal Title
- Cancer Research and Treatment
- Volume
- 54
- Number
- 1
- Start Page
- 1
- End Page
- 9
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84260
- DOI
- 10.4143/crt.2021.1115
- ISSN
- 1598-2998
- Abstract
- Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology. With implementation of NGS in daily clinic, the needs for continued education, facilitated interpretation of NGS results and optimal treatment delivery based on NGS results have been addressed. Molecular tumor board (MTB) is multidisciplinary approach to keep pace with the growing knowledge of complex molecular alterations in patients with advanced solid cancer. Although guidelines for NGS use and MTB have been developed in western countries, there is limitation for reflection of Korea’s public health environment and daily clinical practice. These recommendations provide a critical guidance from NGS panel testing to final treatment decision based on MTB discussion.
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