Low-Osmolar vs. Iso-Osmolar Contrast Media on the Risk of Contrast-Induced Acute Kidney Injury: A Propensity Score Matched Study
DC Field | Value | Language |
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dc.contributor.author | Lee, Taeho | - |
dc.contributor.author | Kim, Won Ki | - |
dc.contributor.author | Kim, Ae Jin | - |
dc.contributor.author | Ro, Han | - |
dc.contributor.author | Chang, Jae Hyun | - |
dc.contributor.author | Lee, Hyun Hee | - |
dc.contributor.author | Chung, Wookyung | - |
dc.contributor.author | Jung, Ji Yong | - |
dc.date.accessioned | 2022-06-03T05:40:26Z | - |
dc.date.available | 2022-06-03T05:40:26Z | - |
dc.date.created | 2022-06-03 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 2296-858X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84502 | - |
dc.description.abstract | Objective:Among the various risk factors associated with contrast-induced acute kidney injury (CI-AKI), the importance of osmolality and viscosity is emerging among the characteristics of contrast media (CM) itself. High osmolality CM (HOCM) is deprecated and low osmotic pressure (LOCM) and iso-osmotic pressure (IOCM) are mainly used in clinical situations where the results of studies on their effect on the development of CI-AKI are contradictory. We evaluated the association between the type of CM and the risk of CI-AKI. Materials and MethodsA retrospective observational cohort study to analyze the effect of the type of CM on the development of CI-AKI. Using propensity score (PS) matching, 2,263 LOCM and IOCM groups were paired for analysis from 5,267 patients and fulfilled the inclusion criteria among 12,742 patients who underwent CAG between 1 January 2007, and 31 December 2016. LOCM included iopromide and iopamidol, IOCM was iodixanol. CI-AKI, which was the primary endpoint, was defined based on the Kidney Disease Improving Global Outcomes criteria within 48 h after exposure to the CM. A multivariable logistic regression analysis was used in the unmatched and matched cohorts, respectively. In addition, a stratified model on clinically important variables, including a high Mehran score (>= 6), was also used in the matched cohort. ResultsLOCM users showed an increased incidence of CI-AKI (11.7% vs. 9.3%; p = 0.006), but it lost statistical significance after PS matching (9.9% vs. 9.5%, p = 0.725). In multivariable analyses, the adjusted odds ratio for CI-AKI in the LOCM group were 1.059 [95% confidence interval (CI) = 0.875-1.282; p = 0.555] in unmatched cohort and 0.987 (95% CI = 0.803-1.214; p = 0.901) in matched cohort. These results were also consistent with the high-risk (high Mehran score) group. ConclusionsAlthough the role of CM types in the development of CI-AKI has been debated, our observation shows that the selection between LOCM and IOCM during CAG has no influence on the incidence of CI-AKI. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.relation.isPartOf | FRONTIERS IN MEDICINE | - |
dc.title | Low-Osmolar vs. Iso-Osmolar Contrast Media on the Risk of Contrast-Induced Acute Kidney Injury: A Propensity Score Matched Study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000796198400001 | - |
dc.identifier.doi | 10.3389/fmed.2022.862023 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN MEDICINE, v.9 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85130293449 | - |
dc.citation.title | FRONTIERS IN MEDICINE | - |
dc.citation.volume | 9 | - |
dc.contributor.affiliatedAuthor | Lee, Taeho | - |
dc.contributor.affiliatedAuthor | Kim, Won Ki | - |
dc.contributor.affiliatedAuthor | Kim, Ae Jin | - |
dc.contributor.affiliatedAuthor | Ro, Han | - |
dc.contributor.affiliatedAuthor | Chang, Jae Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Hee | - |
dc.contributor.affiliatedAuthor | Chung, Wookyung | - |
dc.contributor.affiliatedAuthor | Jung, Ji Yong | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | contrast media (CM) | - |
dc.subject.keywordAuthor | osmolality | - |
dc.subject.keywordAuthor | acute kidney injury (AKI) | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordAuthor | contrast-induced acute kidney injury (CI-AKI) | - |
dc.subject.keywordAuthor | propensity score matching | - |
dc.subject.keywordPlus | PERCUTANEOUS CORONARY INTERVENTION | - |
dc.subject.keywordPlus | INDUCED NEPHROPATHY | - |
dc.subject.keywordPlus | RENAL-INSUFFICIENCY | - |
dc.subject.keywordPlus | IODIXANOL | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | ANGIOGRAPHY | - |
dc.subject.keywordPlus | VISCOSITY | - |
dc.subject.keywordPlus | NEPHROTOXICITY | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | FAILURE | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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