한약제제의 골성장 효과에 대한 국내외 실험 연구 고찰A Literature Review of Experimental Study about Herbal Medicine for Bone Growth
- Other Titles
- A Literature Review of Experimental Study about Herbal Medicine for Bone Growth
- Authors
- 김태정; 김동연; 양희원; 최동건; 권나연; 이동녕; 성현경
- Issue Date
- Aug-2021
- Publisher
- 대한한방소아과학회
- Keywords
- Bone Growth; Pediatric Growth; Herbal Medicine Treatment; Experimental study
- Citation
- 대한한방소아과학회지, v.35, no.3, pp.1 - 27
- Journal Title
- 대한한방소아과학회지
- Volume
- 35
- Number
- 3
- Start Page
- 1
- End Page
- 27
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84599
- ISSN
- 1226-8038
- Abstract
- Objectives The purpose of this study is to investigate the effect of herbal medicine on bone growth and growth factors by collecting and analyzing domestic and foreign experimental research papers to establish a platform for future research.
Methods Experimental studies published before March 2021 were searched using 7 Korean databases and 2 foreign databases. Among the numbers of studies searched, 48 experimental studies met the criteria and were selected. The results of those 48 studies upon herbal medicine administration were analyzed by bone growth, growth plate, weight.
Results 23 studies mainly used monotherapy of either Astragali Radix and Cervi Parvum Cornu. 28 studies used combination of Poria Sclerotium, Dioscoreae Rhizoma, and Acanthopanacis Cortex. Among all studies selected, weight, bone growth, Insulin-like growth factor-1 (IGF-1) and Growth hormone (GH) were increased, but the increase was significant only in some of the studies.
Conclusions The result of this study can be utilized as a background information for further studies and treatment in pediatric growth. Further randomized control studies are needed to underscore the finding.
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