담낭암 성차에 관한 절제가능성 및 조직병리학적 예후-국내 다기관 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박양태 | - |
dc.contributor.author | 강진형 | - |
dc.contributor.author | 김재선 | - |
dc.contributor.author | 정민규 | - |
dc.contributor.author | 김성훈 | - |
dc.contributor.author | 조재희 | - |
dc.contributor.author | 우상명 | - |
dc.contributor.author | 이경주 | - |
dc.contributor.author | 김의주 | - |
dc.contributor.author | 김효정 | - |
dc.date.accessioned | 2022-10-18T01:40:24Z | - |
dc.date.available | 2022-10-18T01:40:24Z | - |
dc.date.created | 2022-10-17 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.issn | 1976-3573 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/85777 | - |
dc.description.abstract | Background/Aim: In gallbladder cancer (GBC), gender differences in incidence and mortality rates have been reported with geographic variation. However, there is little known about sex-related difference in GBC prognosis. This study compares prognostic factors according to gender for GBC. Methods: We searched clinicopathological factors in all stages of 952 GBC patients from seven medical centers in Korea. A total of 927 patients were enrolled and surgery with curative resection was performed in 499 patients. Results: Carbohydrate antigen (≥37 U/mL) was a significant prognostic factor in both females and males (odd ratio [OR], 4.30; 95% confidence interval [CI], 3.13-5.89; p<0.001). Age was a significant factor only in female patients, elderly patients were associated with low resectability and the likelihood of T-stage >2; an independent predictor of poor prognosis via multivariate analysis (OR, 1.03; 95% CI, 1.01-1.05; p=0.005, OR, 1.05; 95% CI, 1.02-1.08; p=0.002). Body mass index (BMI) also showed gender difference, and lower BMI (≤25 kg/m2) was the significant good indicator of multivariate analysis for lymph node metastasis in female patients (OR, 0.42; 95% CI, 0.23-0.77; p=0.005) but, the significant poor indicator of univariate analysis for advanced T-stage in male (OR, 2.79; 95% CI, 1.40-5.54; p=0.003). Conclusions: These results suggest that there is a possibility of gender difference in GBC prognosis. Age and high BMI were poor prognostic factors for curative resection for female GBC patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한췌장담도학회 | - |
dc.relation.isPartOf | 대한췌담도학회지 | - |
dc.title | 담낭암 성차에 관한 절제가능성 및 조직병리학적 예후-국내 다기관 연구 | - |
dc.title.alternative | Multi-Center Study on Gender Difference in Resectability and Pathologic Prognosis of Gallbladder Cancer | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 대한췌담도학회지, v.27, no.3, pp.121 - 127 | - |
dc.identifier.kciid | ART002864892 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 127 | - |
dc.citation.startPage | 121 | - |
dc.citation.title | 대한췌담도학회지 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | 김의주 | - |
dc.subject.keywordAuthor | Gender | - |
dc.subject.keywordAuthor | Age factors | - |
dc.subject.keywordAuthor | Body mass index | - |
dc.subject.keywordAuthor | CA-19-9 antigen | - |
dc.subject.keywordAuthor | Bilirubin | - |
dc.description.journalRegisteredClass | kci | - |
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