The contribution of mouse models to understanding atopic dermatitis
- Authors
- BABINA, SANJEL; Shim, Won-Sik
- Issue Date
- Sep-2022
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Atopic dermatitis; Mouse models; Hapten; Allergen; Bacterial infection; Engineered mouse
- Citation
- BIOCHEMICAL PHARMACOLOGY, v.203
- Journal Title
- BIOCHEMICAL PHARMACOLOGY
- Volume
- 203
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86392
- DOI
- 10.1016/j.bcp.2022.115177
- ISSN
- 0006-2952
- Abstract
- Atopic dermatitis (AD) is a dermatological disease accompanied by dry and cracked skin with severe pruritus. Although various therapeutic strategies have been introduced to alleviate AD, it remains challenging to cure the disorder. To achieve such a goal, understanding the pathophysiological mechanisms of AD is a prerequisite, requiring mouse models that properly reflect the AD phenotypes. Currently, numerous AD mouse models have been established, but each model has its own advantages and weaknesses. In this review, we categorized and summarized mouse models of AD and described their characteristics from a researcher's perspective.
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Collections - 약학대학 > 약학과 > 1. Journal Articles
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