Bone Regeneration Using a Mixture of Silicon-Substituted Coral HA and beta-TCP in a Rat Calvarial Bone Defect Model
DC Field | Value | Language |
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dc.contributor.author | Roh, Jiyeon | - |
dc.contributor.author | Kim, Ji-Youn | - |
dc.contributor.author | Choi, Young-Muk | - |
dc.contributor.author | Ha, Seong-Min | - |
dc.contributor.author | Kim, Kyoung-Nam | - |
dc.contributor.author | Kim, Kwang-Mahn | - |
dc.date.available | 2020-02-28T03:41:19Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-02 | - |
dc.identifier.issn | 1996-1944 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8647 | - |
dc.description.abstract | The demand of bone graft materials has been increasing. Among various origins of bone graft materials, natural coral composed of up to 99% calcium carbonate was chosen and converted into hydroxyapatite (HA); silicon was then substituted into the HA. Then, the Si-HA was mixed with -tricalcium phosphate (TCP) in the ratios 100:0 (S100T0), 70:30 (S70T30), 60:40 (S60T40), and 50:50 (S50T50). The materials were implanted for four and eight weeks in a rat calvarial bone defect model (8 mm). The MBCPTM (HA:-TCP = 60:40, Biomatalante, Vigneux de Bretagne, France) was used as a control. After euthanasia, the bone tissue was analyzed by making histological slides. From the results, S60T40 showed the fastest bone regeneration in four weeks (p < 0.05). In addition, S60T40, S50T50, and MBCPTM showed significant new bone formation in eight weeks (p < 0.05). In conclusion, Si-HA/TCP showed potential as a bone graft material. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | MATERIALS | - |
dc.subject | CALCIUM-PHOSPHATE | - |
dc.subject | CRANIAL DEFECTS | - |
dc.subject | IN-VIVO | - |
dc.subject | HYDROXYAPATITE | - |
dc.subject | GRAFT | - |
dc.subject | BIOCERAMICS | - |
dc.title | Bone Regeneration Using a Mixture of Silicon-Substituted Coral HA and beta-TCP in a Rat Calvarial Bone Defect Model | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000371828100011 | - |
dc.identifier.doi | 10.3390/ma9020097 | - |
dc.identifier.bibliographicCitation | MATERIALS, v.9, no.2 | - |
dc.identifier.scopusid | 2-s2.0-84960092107 | - |
dc.citation.title | MATERIALS | - |
dc.citation.volume | 9 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Kim, Ji-Youn | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | silicon-substituted coral hydroxyapatite | - |
dc.subject.keywordAuthor | beta-tricalcium phosphate | - |
dc.subject.keywordAuthor | bone graft material | - |
dc.subject.keywordAuthor | bone regeneration | - |
dc.subject.keywordAuthor | rat calvarial bone defect model | - |
dc.subject.keywordPlus | CALCIUM-PHOSPHATE | - |
dc.subject.keywordPlus | CRANIAL DEFECTS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | GRAFT | - |
dc.subject.keywordPlus | BIOCERAMICS | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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