Copper-Catalyzed One-Pot Arylation and Cyclization of Diaryliodonium Salts Derived from o-Iodoanilines for Indolo[2,3-b]indoles Syntheses

Abstract

One-pot synthesis of various indolo[2,3-b]indoles has been accomplished from a copper-catalyzed transformation of easily accessible 2-(substituted-amino)aryl)(mesityl)iodonium salts and indole derivatives. Reaction offers great functional group toleration, providing a series of indolo[2,3-b]indole derivatives in good yields. Additionally, intramolecular cyclization of 2-(substituted-amino)aryl)(mesityl)iodonium salts in the presence of copper-catalyst provided direct access to benzoxazole derivatives. © 2022 Wiley-VCH GmbH.