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MXenes-Versatile 2D materials for identification of biomarkers and contaminants in large scale environments-A review

Authors
Chandrasekar, NarendharSteffi, Alexander PinkyRamachandran, BalajiHwang, Michael TaeyoungFaramarzi, VahidGovarthanan, Muthusamy
Issue Date
Jul-2023
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Keywords
MXenes; 2d nanomaterials; Biosensors; SARS-COV-2 nucleocapsid sensors; Environmental pollutant detection
Citation
ENVIRONMENTAL RESEARCH, v.228
Journal Title
ENVIRONMENTAL RESEARCH
Volume
228
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/87926
DOI
10.1016/j.envres.2023.115900
ISSN
0013-9351
Abstract
Recent years have seen a lot of interest in transition metal carbides/carbonitrides (MXenes), Which is one of newly proliferating two-dimensional (2D) materials.The advantages and applications of synthesizing MXenes-based biosensing systems are interesting. There is an urgent requirement for synthesis of MXenes. Through foliation, physical adsorption, and interface modification,it has been proposed that many biological disorders are related to genetic mutation. Majority of mutations were discovered to be nucleotide mismatches. Consequently, accurate-nucleotide mismatched discrimination is crucial for both diagnosing and treating diseases. To differ-entiate between such a sensitivealterations in the DNA duplex, several detection methods, particularly Electrochemical-luminescence (ECL) ones, have really been investigated.Mn+1XnTx is common name for MXenes, a novel family of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, where T stands for interface termination units (i.e. = O, OH, and/or F). These electronic characteristics of MXenes may be changed between conductive to semiconducting due to abundant organometallic chemistry.Solid-state ECL sensors predicated on MXene would provide the facile nucleotide detection and convenience for usage with minimal training, mobility and possibly minimal cost.This study emphasizes upcoming requirements and possibilities in this area while describing the accomplishments achieved in the usage and employing of MXenes in the research and development of facile biomarkerdetection and their significance in designing electrochemical sensors. Op-portunities are addressed for creating 2D MXene materials sensors and devices with incorporated biomolecule sensing. MXenes Carry out this process sensors, address the advantages of using MXenes and their variants as detecting materials for gathering different types of data, and attempt to clarify the design principles and oper-ation of related MXene-based sensors, such as nucleotide detection, Single nucleotide detectors, Cancer thera-nostics, Biosensing capabilities, Gliotoxin detection, SARS-COV-2 nucleocapsid detection, electrochemical sensors, visual sensors, and humidity sensors. Finally, we examine the major issues and prospects for MXene-based materials used in various sensing applications.
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