Nanotechnology-Based Promising Therapeutic Approaches Against Protozoan
- Authors
- Raghav, A.; Ansari, S.K.; Singh, A.K.; Tripathi, P.; Agarwal, S.; Giri, R.; Ali, S.G.; Khan, H.M.
- Issue Date
- Feb-2023
- Publisher
- Springer Nature
- Keywords
- Exosomes; Liposomes; Nano-vaccines; Nanoparticles; Nanopharmaceuticals; Protozoan disease; Therapeutics
- Citation
- Pathobiology of Parasitic Protozoa: Dynamics and Dimensions, pp.1 - 18
- Journal Title
- Pathobiology of Parasitic Protozoa: Dynamics and Dimensions
- Start Page
- 1
- End Page
- 18
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88113
- DOI
- 10.1007/978-981-19-8225-5_1
- ISSN
- 0000-0000
- Abstract
- Protozoan-borne diseases are major drivers of global morbidities and mortalities, especially in developing countries. These diseases pose a unique challenge to effective treatment strategies, thereby contributing to significant death. Current treatment approaches have low efficacy, high toxicity and side effects of therapeutic doses and therefore generate a need for alternative new treatment approaches. Nanotechnology-based drug delivery systems have evolved as a new and promising approach to therapy and prevention of protozoan-associated infectious diseases. The formulation of new drugs and drugs’ carriers using nano-sized particles including exosomes, liposomes, solid lipid nanoparticles, dendrimers and nano-vaccines promises to overcome the limitations of low bioavailability, low toxicity, sub-therapeutic drug accumulation in microbial sanctuaries and reservoirs and low patient adherence due to drug-related toxicities and extended therapeutic regimens. Nanotechnology-based therapeutic approaches offer an important weapon in the fight against infectious protozoan diseases. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023.
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