Fabrication of an Electrocatalyst Based on Rare Earth Manganites Incorporated with Carbon Nanofiber Hybrids: An Efficient Electrochemical Biosensor for the Detection of Anti-Inflammatory Drug Mefenamic Acidopen access
- Authors
- Alagarsamy, Saranvignesh; Sundaresan, Ruspika; Chen, Shen-Ming; Devi, J. Meena; Chandrasekar, Narendhar; Ramachandran, Balaji
- Issue Date
- Jun-2023
- Publisher
- MDPI
- Keywords
- rare earth manganites; carbon nanofiber; mefenamic acid; anti-inflammatory drug; hydrothermal
- Citation
- C-JOURNAL OF CARBON RESEARCH, v.9, no.2
- Journal Title
- C-JOURNAL OF CARBON RESEARCH
- Volume
- 9
- Number
- 2
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88577
- DOI
- 10.3390/c9020047
- ISSN
- 2311-5629
2311-5629
- Abstract
- Pharmaceutical and personal care products are emerging as a new category of environmental pollution. Analytical drug detection from a biological sample for detection is still crucial today. Mefenamic acid (MA) is an anti-inflammatory drug utilized for its antipyretic and analgesic properties, which is harmful to patients at higher dosages and is also recognized as a chemical pollutant that harms the environment. In this view, Dysprosium manganite/carbon nanofiber (DMO/CNF) was prepared by hydrothermal method for the electrochemical detection of MA. DMO/CNF/GCE exhibits high selectivity, excellent anti-interference, good stability, and reproducibility toward the detection of MA. The enhanced electrochemical performance of DMO/CNF/GCE was attributed to their synergetic interaction. Under optimized conditions, DMO/CNF/GCE shows a wide linear range of 0.01-741 & mu;M and a low LOD of 0.009 & mu;M. Satisfactory recoveries were obtained for human blood and tablet samples. Thus, the proposed DMO/CNF nanocomposite emerges as a promising material for the detection of MA.
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