Automated Laser-Fiber Coupling Module for Optical-Resolution Photoacoustic Microscopyopen access
- Authors
- Han, Seongyi; Kye, Hyunjun; Kim, Chang-Seok; Kim, Tae-Kyoung; Yoo, Jinwoo; Kim, Jeesu
- Issue Date
- Jul-2023
- Publisher
- MDPI
- Keywords
- photoacoustic microscopy; laser delivery; optical fiber; laser-fiber coupling
- Citation
- SENSORS, v.23, no.14
- Journal Title
- SENSORS
- Volume
- 23
- Number
- 14
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88828
- DOI
- 10.3390/s23146643
- ISSN
- 1424-8220
- Abstract
- Photoacoustic imaging has emerged as a promising biomedical imaging technique that enables visualization of the optical absorption characteristics of biological tissues in vivo. Among the different photoacoustic imaging system configurations, optical-resolution photoacoustic microscopy stands out by providing high spatial resolution using a tightly focused laser beam, which is typically transmitted through optical fibers. Achieving high-quality images depends significantly on optical fluence, which is directly proportional to the signal-to-noise ratio. Hence, optimizing the laser-fiber coupling is critical. Conventional coupling systems require manual adjustment of the optical path to direct the laser beam into the fiber, which is a repetitive and time-consuming process. In this study, we propose an automated laser-fiber coupling module that optimizes laser delivery and minimizes the need for manual intervention. By incorporating a motor-mounted mirror holder and proportional derivative control, we successfully achieved efficient and robust laser delivery. The performance of the proposed system was evaluated using a leaf-skeleton phantom in vitro and a human finger in vivo, resulting in high-quality photoacoustic images. This innovation has the potential to significantly enhance the quality and efficiency of optical-resolution photoacoustic microscopy.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88828)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.