국내 성인 알레르겐 감작률과 Geographic Information System 기반 공간분석을 활용한 지역별 감작률 연구open accessMultiple allergen simultaneous test is useful in assessing allergen sensitization and its geographic variations by the Geographic Information System-based approach
- Other Titles
- Multiple allergen simultaneous test is useful in assessing allergen sensitization and its geographic variations by the Geographic Information System-based approach
- Authors
- 강성윤; 권재우; 임정훈; 김형년; 정성근; 정재원
- Issue Date
- Jul-2023
- Publisher
- 대한 소아알레르기 호흡기학회
- Keywords
- Allergens; Sensitization; Multiple allergen simultaneous test; Geographic Information System; .
- Citation
- Allergy Asthma & Respiratory Disease, v.11, no.3, pp.135 - 143
- Journal Title
- Allergy Asthma & Respiratory Disease
- Volume
- 11
- Number
- 3
- Start Page
- 135
- End Page
- 143
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88946
- DOI
- 10.4168/aard.2023.11.3.135
- ISSN
- 2288-0402
- Abstract
- Purpose: To evaluate allergen sensitization in Koreans and assess regional differences in it using Geographic Information System (GIS)-based modeling techniques.
Methods: We retrospectively analyzed multiple allergen simultaneous test (MAST) results collected from 2,017 clinics and hospitals nationwide between 2018 and 2020. The AdvanSureTM AlloScreen (LG Chem, Seoul, Korea) was used to test for 47 allergens. Then, we created maps to visualize the sensitization prediction rate by using the ordinary kriging method.
Results: The total number of participants were 196,419; 104,371 (53.1%) were sensitized to one or more allergens. The most frequent allergen causing sensitization was Dermatophagoides farinae (34.0%), followed by Dermatophagoides pteronyssinus (32.3%), house dust (26.2%), cat dander (13.6%), Acarus siro (12.5%), rye grass pollen (8.8%), and birch tree pollen (8.2%), respectively. Perennial allergens, such as mites and cat dander, were more common than seasonal allergens. Sensitization rates to grasses were generally higher than those to tree and weed allergens. The sensitization rates to Hymenoptera venoms were 4.8% in honey bee and 2.2% in yellow jacket. The sensitization prediction rate against Dermatophagoides farinae calculated by GIS-based mapping showed geographical differences even within the same administrative district.
Conclusion: Dermatophagoides farinae and Dermatophagoides pteronyssinus were found to be the most prevalent sensitizing allergens throughout Korea. GIS-based spatial pattern analysis using MAST revealed different sensitization patterns between geographic areas and at the subdistrict level. These data could assist in prevention and management of allergic diseases and provide valuable evidence for environmental and public health policymakers.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88946)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.