Korea Seroprevalence Study of Monitoring of SARS-COV-2 Antibody Retention and Transmission (K-SEROSMART): findings from national representative sampleopen access
- Authors
- Han, Jina; Baek, Hye Jin; Noh, Eunbi; Yoon, Kyuhyun; Kim, Jung Ae; Ryu, Sukhyun; Lee, Kay O.; Park, No Yai; Jung, Eunok; Kim, Sangil; Lee, Hyukmin; Hwang, Yoo-Sung; Jung, Jaehun; Lee, Hun Jae; Cho, Sung-il; Oh, Sangcheol; Kim, Migyeong; Oh, Chang-Mo; Yu, Byengchul; Hong, Young-Seoub; Kim, Keonyeop; Jung, Sunjae; Han, Mi Ah; Lee, Moo-Sik; Lee, Jung-Jeung; Hwangbo, Young; Yim, Hyeon Woo; Kim, Yu-Mi; Lee, Joongyub; Lee, Weon-Young; Park, Jae-Hyun; Oh, Sungsoo; Jo, Heui Sug; Kim, Hyeongsu; Kang, Gilwon; Nam, Hae-Sung; Lee, Ju-Hyung; Oh, Gyung-Jae; Shin, Min-Ho; Ryu, Soyeon; Hwang, Tae-Yoon; Park, Soon-Woo; Kim, Sang Kyu; Seol, Roma; Park, Ki-Soo; Kim, Su Young; Kwon, Jun-wook; Kim, Sung Soon; Kim, Byoungguk; Lee, June-Woo; Jang, Eun Young; Kim, Ah-Ra; Nam, Jeonghyun; Lee, Soon Young; Kim, Dong-Hyun
- Issue Date
- Aug-2023
- Publisher
- KOREAN SOC EPIDEMIOLOGY
- Keywords
- COVID-19; Seroepidemiologic studies; Antibody; Community Health Survey; Sampling studies
- Citation
- EPIDEMIOLOGY AND HEALTH, v.45, pp 1 - 13
- Pages
- 13
- Journal Title
- EPIDEMIOLOGY AND HEALTH
- Volume
- 45
- Start Page
- 1
- End Page
- 13
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/89644
- DOI
- 10.4178/epih.e2023075
- ISSN
- 1225-3596
2092-7193
- Abstract
- OBJECTIVES: We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention and Transmission (K-SEROSMART) in 258 communities throughout Korea.METHODS: In August 2022, a survey was conducted among 10,000 household members aged 5 years and older, in households selected through two stage probability random sampling. During face-to-face household interviews, participants self-reported their health status, COVID-19 diagnosis and vaccination history, and general characteristics. Subsequently, participants visited a community health center or medical clinic for blood sampling. Blood samples were analyzed for the presence of antibodies to spike proteins (anti-S) and antibodies to nucleocapsid proteins (anti-N) SARS-CoV-2 proteins using an electrochemiluminescence immunoassay. To estimate the population prevalence, the PROC SURVEYMEANS statistical procedure was employed, with weighting to reflect demographic data from July 2022.RESULTS: In total, 9,945 individuals from 5,041 households were surveyed across 258 communities, representing all basic local governments in Korea. The overall population-adjusted prevalence rates of anti-S and anti-N were 97.6% and 57.1%, respectively. Since the Korea Disease Control and Prevention Agency has reported a cumulative incidence of confirmed cases of 37.8% through July 31, 2022, the proportion of unreported infections among all COVID-19 infection was suggested to be 33.9%.CONCLUSIONS: The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19, confirming that most individuals possess antibodies to SARS-CoV-2 and that a significant number of unreported cases existed. Furthermore, this study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/89644)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.