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스테로이드 치료에 반응을 보인 과관류를 동반한 급성기 멜라스증후군An Acute Metabolic Encephalopathy, Lactic Acidosis and Stroke-like Episodes Syndrome Patients with Hyperperfusion Responsive to Steroid Treatment
- Other Titles
- An Acute Metabolic Encephalopathy, Lactic Acidosis and Stroke-like Episodes Syndrome Patients with Hyperperfusion Responsive to Steroid Treatment
- Issue Date
- Nov-2023
- Publisher
- 대한신경과학회
- Keywords
- MELAS syndrome; Cerebral blood flow; Steroids
- Citation
- 대한신경과학회지, v.41, no.4, pp 306 - 309
- Pages
- 4
- Journal Title
- 대한신경과학회지
- Volume
- 41
- Number
- 4
- Start Page
- 306
- End Page
- 309
- ISSN
- 1225-7044
2288-985X
- Abstract
- Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a genetic disorder caused by mutation in mitochondrial DNA. Patients with stroke-like episodes show restrictive lesions in diffusion weighted image, whereas magnetic resonance angiography images show both vasodilation or vasoconstriction. Vasodilation may lead to hyperperfusion and cerebral edema, which may worsen clinical outcome. Here, we report a 25-year-old male patient diagnosed as MELAS, who presented with stroke-like episodes and seizures and showed cerebral edema with vasodilation which was normalized after steroid treatment.
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