소아에서 계절성 인플루엔자의 신경학적 또는 신경근육 합병증

Abstract

Purpose: Influenza is generally known cause of acute respiratory disease. It is also cause of neurologic complications and has seldom non-benign nature. We report our cases of neurologic complications with influenza infection among children in 2013 seasonal endemic, and debate on benign nature of seasonal influenza. Methods: We retrospectively reviewed the medical records of all children who were confirmed influenza infection at the Konyang University Hospital, between December 2013 and March 2014. Results: A total of 279 children had influenza infections and 17 (6.1%) presented with neurologic complications. Eight patients manifested febrile seizures, one presented status epilepticus due to with aggravation of epilepsy, and seven presented with myositis. Influenza-associated encephalitis and optic neuritis were observed in each one patient. Most patients showed mild and benign progress, however the patient with influenza-associated encephalitis suffered severe complications. Conclusion: Children with seasonal influenza infections presented a wide spectrum of neurologic manifestations usually in young children. We recommend to suspect the possibility of influenza infection in the diagnosis of children manifesting neurologic symptoms during influenza epidemics.