Advancement in COVID-19 detection using nanomaterial-based biosensors
- Authors
- Truong, Phuoc Loc; Yin, Yiming; Lee, Daeho; Ko, Seung Hwan
- Issue Date
- Feb-2023
- Publisher
- John Wiley & Sons Inc
- Keywords
- colorimetric biosensor; COVID-19 detection; electrochemical biosensor; field-effect transistor biosensor; mass spectroscopy; plasmonic biosensor
- Citation
- Exploration, v.3, no.1
- Journal Title
- Exploration
- Volume
- 3
- Number
- 1
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90530
- DOI
- 10.1002/EXP.20210232
- ISSN
- 2766-8509
- Abstract
- Coronavirus disease 2019 (COVID-19) pandemic has exemplified how viral growth and transmission are a significant threat to global biosecurity. The early detection and treatment of viral infections is the top priority to prevent fresh waves and control the pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified through several conventional molecular methodologies that are time-consuming and require high-skill labor, apparatus, and biochemical reagents but have a low detection accuracy. These bottlenecks hamper conventional methods from resolving the COVID-19 emergency. However, interdisciplinary advances in nanomaterials and biotechnology, such as nanomaterials-based biosensors, have opened new avenues for rapid and ultrasensitive detection of pathogens in the field of healthcare. Many updated nanomaterials-based biosensors, namely electrochemical, field-effect transistor, plasmonic, and colorimetric biosensors, employ nucleic acid and antigen–antibody interactions for SARS-CoV-2 detection in a highly efficient, reliable, sensitive, and rapid manner. This systematic review summarizes the mechanisms and characteristics of nanomaterials-based biosensors for SARS-CoV-2 detection. Moreover, continuing challenges and emerging trends in biosensor development are also discussed. © 2023 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd.
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