A Wearable ECG Monitoring System Using Microneedle Electrodes for Small Animals
DC Field | Value | Language |
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dc.contributor.author | Kim, Chaehyun | - |
dc.contributor.author | Jang, Ahram | - |
dc.contributor.author | Kim, Sebin | - |
dc.contributor.author | Cho, Sungbo | - |
dc.contributor.author | Lee, Donghun | - |
dc.contributor.author | Kim, Young-Joon | - |
dc.date.accessioned | 2024-03-08T08:01:24Z | - |
dc.date.available | 2024-03-08T08:01:24Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 1530-437X | - |
dc.identifier.issn | 1558-1748 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90577 | - |
dc.description.abstract | The electrocardiogram (ECG) is an effective tool for monitoring various health conditions, and animal studies using ECG have uncovered new information about complex diseases. However, monitoring electrophysio-logical signals in small animals such as mice has been challenging. In this study, we present a simple, minimally invasive, and inexpensive ECG measurement sensory system for mice that offers real-time data acquisition while performing a surgery. We developed a miniaturized, wearable ECG monitoring device that utilizes miniature-sized, rigid metal-type microneedle electrodes with a skin-electrode contact resistivity of 20 kΩ at 10 Hz, which is lower than commercial Ag/AgCl electrodes used in human ECGs. The device, excluding the battery, is less than 50 cubic millimeters in size and amplifies and converts the waveform which is transmitted to a personal cell phone or laptop. We developed a smartphone application to display the real-time ECG waveform and heart rate without the need for additional equipment. The recorded data can be retrieved for further analysis, and the real-time display feature can be used to monitor an animal’s condition during surgery. We validated this method by inducing a photothrombotic stroke in an ICR mouse to study ECG and HR parameters in an animal stroke model. IEEE | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Institute of Electrical and Electronics Engineers Inc. | - |
dc.title | A Wearable ECG Monitoring System Using Microneedle Electrodes for Small Animals | - |
dc.type | Article | - |
dc.identifier.wosid | 001090399700142 | - |
dc.identifier.doi | 10.1109/JSEN.2023.3300992 | - |
dc.identifier.bibliographicCitation | IEEE Sensors Journal, v.23, no.18, pp 21873 - 21881 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85166744675 | - |
dc.citation.endPage | 21881 | - |
dc.citation.startPage | 21873 | - |
dc.citation.title | IEEE Sensors Journal | - |
dc.citation.volume | 23 | - |
dc.citation.number | 18 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | electrocardiogram | - |
dc.subject.keywordAuthor | microneedle electrode | - |
dc.subject.keywordAuthor | real-time monitoring | - |
dc.subject.keywordAuthor | wearable device | - |
dc.subject.keywordPlus | ARRAY ELECTRODE | - |
dc.subject.keywordPlus | ELECTROCARDIOGRAM | - |
dc.subject.keywordPlus | MICE | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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