국내산 桑枝의 품질관리 연구Studies on quality control of domestic Morus alba Linne
- Other Titles
- Studies on quality control of domestic Morus alba Linne
- Authors
- 박유미; 백미은; 이영종; 원재희
- Issue Date
- 2016
- Publisher
- 대한본초학회
- Keywords
- Morus alba Linne; Quality Control; Oxyresveratrol; TLC
- Citation
- 대한본초학회지, v.31, no.3, pp.71 - 75
- Journal Title
- 대한본초학회지
- Volume
- 31
- Number
- 3
- Start Page
- 71
- End Page
- 75
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9439
- ISSN
- 1229-1765
- Abstract
- Objectives : Mori Ramulus is a young branch of Morus alba Linne, which has been used as traditional medicines for antidiarrhea, antibacteria, and antihypertension in Korea. With the basis on these medicinal activities, it is registered at the Korean Herbal Pharmacopoeia. The standard for quality control in use, however, is not yet validated.
Methods : We experiment on heavy metals test, TLC, loss on drying, ash, acid-insoluble ash, contents of ethanol- soluble extracts and contents of oxyresveratrol by using the 15 samples of Mori Ramulus which are collected domestically. We tested items according to the General Test, processes and apparatus, Crude Drugs Test of KP(2011).
Results : Purity test(Heavy metals) showed contents for Pb, As, Hg, and Cd range of 0.1~1.1 ppm, 0.0~0.2 ppm, 0.00~0.01 ppm, and 0.00~0.02 ppm. Identification test(Thin layer chromatography) was on comparing with morucine standard solution in Rf value, all samples showed morucine spot (dark blue, Rf : 0.3) as same as Rf value of morucine-standard solution. Loss on drying was ranged from 5.1 to 8.9 %, ash and acid-insoluble ash were between the range 3.0~6.3% and 0.3~0.8%. Contents of ethanol-soluble extracts was ranged from 6.2 to 12.0%. Content of oxyresveratrol was ranged from 0.01 to 0.16 % based on the oxyresveratrol standard curve.
Conclusions : We sincerely hope that this study will be contributed to the standardization and quality control of Korean herbal medicines.
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