梔子가 JNK와 NF-kB를 통한 항산화와 항염증의 대사과정에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상철 | - |
dc.contributor.author | 심성용 | - |
dc.contributor.author | 김연섭 | - |
dc.date.available | 2020-02-28T05:43:45Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1738-6640 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9442 | - |
dc.description.abstract | Objectives : The purpose of this study is to observe the effects of Gardeniae Fuctus(GF) on the metabolic process of antioxidant and anti-inflammation. Methods : 4-HNE was injected into PC-12 cell to cause oxidative stress-induced inflammatory response, and then a western blot was conducted to observe the expression of Nuclear Factor-kB (NF-kB) and c-Jun N-terminal kinase (JNK) protein that are important factors involved with inflammation. Results : 1. The Gardeniae Fuctus water extract 50 ㎍ and 100 ㎍ significantly suppressed the increase in JNK protein expression in PC-12 cell. 2. The Gardeniae Fuctus water extract 50 ㎍, 100 ㎍ and 200 ㎍ significantly suppressed the increase in NF-kB protein expression in PC-12 cell. Conclusion : These results suggest that the Gardeniae Fuctus water extract has antioxidative and anti-inflammatory activity through suppressing the activity of JNK and NF-kB. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한방안이비인후피부과학회 | - |
dc.relation.isPartOf | 한방안이비인후피부과학회지 | - |
dc.title | 梔子가 JNK와 NF-kB를 통한 항산화와 항염증의 대사과정에 미치는 영향 | - |
dc.title.alternative | Effects of Gardeniae Fructus on the metabolic process of antioxidant and anti-inflammation by JNK and NF-kB | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.6114/jkood.2016.29.2.056 | - |
dc.identifier.bibliographicCitation | 한방안이비인후피부과학회지, v.29, no.2, pp.56 - 64 | - |
dc.identifier.kciid | ART002108371 | - |
dc.citation.endPage | 64 | - |
dc.citation.startPage | 56 | - |
dc.citation.title | 한방안이비인후피부과학회지 | - |
dc.citation.volume | 29 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 이상철 | - |
dc.contributor.affiliatedAuthor | 심성용 | - |
dc.contributor.affiliatedAuthor | 김연섭 | - |
dc.subject.keywordAuthor | Gardeniae Fuctus | - |
dc.subject.keywordAuthor | 4-HNE | - |
dc.subject.keywordAuthor | JNK | - |
dc.subject.keywordAuthor | NF-kB | - |
dc.description.journalRegisteredClass | kci | - |
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