임신쥐 출산 전 유산소 운동량에 따른 Adiponectin과 PPAR-γ유전자의 발현

Abstract

This study got supplied ICR mice(7 week old), male(n=14), female(n=70) at Animal handling companies. After hybridization, It was selected pregnant mice and into 3 groups depending on exercise amount; no exercise group(n=15), low exercise group(n=15), mid exercise group(n=15), high exercise group(n=15). A series of genetic tests were performed to identify adiponectin and PPAR-γgene expression producing the following results. Although there were no significant statistical differences when comparing the “low exercise” group, mid exercise group and high exercise group, adiponectin expression within the liver showed notable statistical differences when comparing the no exercise group to the mid exercise group(p<.05) and the no exercise group to the high exercise group(p<.01). Statistical changes were noted for PPAR-γexpression showed statistical changes in the “no exercise” group and high exercise group(p<.05). In conclusion it was found that the right amount of pre/postnatal exercise can prove to be beneficial. Therefore, moderate exercise time before the birth of adiponectin, the more momentum increases the expression of PPAR-γgene was increased.