PHENOLIC DERIVATIVES FROM THE STEMS OF LAGERSTROEMIA INDICA AND THEIR BIOLOGICAL ACTIVITY
- Authors
- Woo, Kyeong Wan; Suh, Won Se; Lalita, Subedi; Kim, Sun Yeou; Choi, Sang Un; Kim, Ki Hyun; Lee, Kang Ro
- Issue Date
- 1-Dec-2015
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Citation
- HETEROCYCLES, v.91, no.12, pp.2355 - 2366
- Journal Title
- HETEROCYCLES
- Volume
- 91
- Number
- 12
- Start Page
- 2355
- End Page
- 2366
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9827
- DOI
- 10.3987/COM-15-13328
- ISSN
- 0385-5414
- Abstract
- The purification of a MeOH extract from the stems of Lagerstroemia indica (Lythraceae) using repeated column chromatography afforded three new phenolic glycosides (1-3), and a new flavone derivative (4) along with fifteen known compounds (5-19). The structures of new compounds were determined through spectral analysis, including 1D, 2D-NMR and MS data. Compounds 1-19 were evaluated for their inhibitory activities on nitric oxide (NO) production in an activated murine microglial cell line and cytotoxic activities against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15).
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