Enzymatic synthesis of 2-deoxyglucose-containing maltooligosaccharides for tracing the location of glucose absorption from starch digestion
DC Field | Value | Language |
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dc.contributor.author | Lee, Byung-Hoo | - |
dc.contributor.author | Koh, Dong-Wan | - |
dc.contributor.author | Territo, Paul R. | - |
dc.contributor.author | Park, Cheon-Seok | - |
dc.contributor.author | Hamaker, Bruce R. | - |
dc.contributor.author | Yoo, Sang-Ho | - |
dc.date.available | 2020-02-28T07:42:44Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-11-05 | - |
dc.identifier.issn | 0144-8617 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9914 | - |
dc.description.abstract | The ileal brake mechanism which induces a potentially beneficial slower gastric emptying rate and increased satiety is triggered by macronutrients including glucose from glycemic carbohydrates. For optimization of this diet-induced health benefit, there is the need for a way to determine the location of glucose deposition in the small intestine. Labeled 2-deoxyglucose (2-DG) can be used to trace the location of glucose absorption due to its accumulative property in the small intestine enterocytes. However, because pure glucose, or 2-DG, is directly absorbed in the proximal small intestine, we designed 2-DG containing maltooligosaccharides (2-DG-MOs) that can be used with a mild alpha-glucosidase inhibitor to attain an analytical method for determining location-specific delivery of glucose and its physiological effect. (C) 2015 Elsevier Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.relation.isPartOf | CARBOHYDRATE POLYMERS | - |
dc.subject | MALTASE-GLUCOAMYLASE ACTIVITY | - |
dc.subject | NEISSERIA-POLYSACCHAREA | - |
dc.subject | SUCRASE-ISOMALTASE | - |
dc.subject | BARLEY STARCHES | - |
dc.subject | SUBSTRATE BRAKE | - |
dc.subject | AMYLOSUCRASE | - |
dc.subject | TRANSPORT | - |
dc.subject | SUCROSE | - |
dc.subject | BINDING | - |
dc.subject | GLUT2 | - |
dc.title | Enzymatic synthesis of 2-deoxyglucose-containing maltooligosaccharides for tracing the location of glucose absorption from starch digestion | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000361184900006 | - |
dc.identifier.doi | 10.1016/j.carbpol.2015.06.012 | - |
dc.identifier.bibliographicCitation | CARBOHYDRATE POLYMERS, v.132, pp.41 - 49 | - |
dc.identifier.scopusid | 2-s2.0-84934293380 | - |
dc.citation.endPage | 49 | - |
dc.citation.startPage | 41 | - |
dc.citation.title | CARBOHYDRATE POLYMERS | - |
dc.citation.volume | 132 | - |
dc.contributor.affiliatedAuthor | Lee, Byung-Hoo | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | 2-Deoxyglucose (2-DG) | - |
dc.subject.keywordAuthor | Amylosucrase | - |
dc.subject.keywordAuthor | Glucose absorption | - |
dc.subject.keywordAuthor | Maltooligosaccharides | - |
dc.subject.keywordAuthor | Mucosal alpha-glucosidases | - |
dc.subject.keywordPlus | MALTASE-GLUCOAMYLASE ACTIVITY | - |
dc.subject.keywordPlus | NEISSERIA-POLYSACCHAREA | - |
dc.subject.keywordPlus | SUCRASE-ISOMALTASE | - |
dc.subject.keywordPlus | BARLEY STARCHES | - |
dc.subject.keywordPlus | SUBSTRATE BRAKE | - |
dc.subject.keywordPlus | AMYLOSUCRASE | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | SUCROSE | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | GLUT2 | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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