A long-term incidence of heart failure and predictors following newly developed acute myocardial infarction: A 10 years retrospective cohort study with korean national health insurance dataopen access
- Authors
- Choi, Hyojung; Seo, Joo Yeon; Shin, Jinho; Choi, Bo Youl; Kim, Yu-Mi
- Issue Date
- Jun-2021
- Publisher
- MDPI AG
- Keywords
- Heart failure; Incidence; Myocardial infarction; Prognosis; Risk factors
- Citation
- International Journal of Environmental Research and Public Health, v.18, no.12, pp.1 - 10
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- International Journal of Environmental Research and Public Health
- Volume
- 18
- Number
- 12
- Start Page
- 1
- End Page
- 10
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/1044
- DOI
- 10.3390/ijerph18126207
- ISSN
- 1661-7827
- Abstract
- Background Heart failure (HF) is the major mechanism of mortality in acute myocardial infarction (AMI) during early or intermediate post-AMI period. But heart failure is one of the most common long-term complications of AMI. Applied the retrospective cohort study design with nation representative population data, this study traced the incidence of late-onset heart failure since 1 year after newly developed acute myocardial infarction and assessed its risk factors. Methods and Results: Using the Korea National Health Insurance database, 18,328 newly developed AMI patients aged 40 years or older and first hospitalized in 2010 for 3 days or more, were set up as baseline cohort (12,403). The incidence rate of AMI per 100,000 persons was 79.8 overall, and 49.6 for women and 112.3 for men. A total of 2010 (1073 men, 937 women) were newly developed with HF during 6 years following post AMI. Cumulative incidences of HF per 1000 AMI patients for a year at each time period were 37.4 in initial hospitalization, 32.3 in 1 year after discharge, and 8.9 in 1-6 years. The overall and age-specific incidence rates of HF were higher in women than men. For late-onset HF, female, medical aid, pre-existing hypertension, severity of AMI, duration of hospital stay during index admission, reperfusion treatment, and drug prescription pattern including diuretics, affected the occurrence of late-onset HF. Conclusion: With respect to late-onset HF following AMI, appropriate management including hypertension and medical aid program in addition to quality improvement of AMI treatment are required to reduce the risk of late-onset heart failure.
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