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A Case of Prosthetic Valve Endocarditis with Cerebral Hemorrhage Caused by Rothia mucilaginosa뇌출혈을 동반한 Rothia mucilaginosa 인공판막 심내막염

Other Titles
뇌출혈을 동반한 Rothia mucilaginosa 인공판막 심내막염
Authors
Song, Yeo-JinKim, BongyoungKim, Young-eunLee, YangsoonPai, Hyunjoo
Issue Date
Dec-2019
Publisher
대한임상미생물학회
Keywords
Cerebral hemorrhage; Infective endocarditis; Prosthetic valve; Rothia mucilaginosa
Citation
Annals of Clinical Microbiology, v.23, no.4, pp 1 - 6
Pages
6
Indexed
KCI
KCICANDI
Journal Title
Annals of Clinical Microbiology
Volume
23
Number
4
Start Page
1
End Page
6
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/11526
DOI
10.5145/ACM.2020.23.4.6
ISSN
2288-0585
2288-6850
Abstract
Rothia spp. are aerobic, gram-positive cocci belonging to the family Micrococcaceae, and are a part of the normal microbial flora of the human oropharynx and upper respiratory tract. We present the first case of the prosthetic valve endocarditis with cerebral hemorrhage caused by Rothia mucilaginosa in South Korea. A 65-year-old man with a prosthetic aortic valve visited the outpatient clinic with a complaint of fever. R. mucilaginosa was identified in one among four sets of blood culture bottles obtained on the on day 30 of fever onset. Brain magnetic resonance imaging (MRI) showed multiple micro-hemorrhages suggesting septic emboli in both the hemispheres, corticomedullary junctions, and cerebellum. Rothia spp. should be considered as a possible pathogen in the cases of infective endocarditis with intracranial hemorrhage.
Rothia 종은 호기성 그람양성구균으로 Micrococcaceae 과에 속하며, 사람의 구인두 및 상부 호흡기의 정상 세균총이다. Rothia mucilaginosa에 의한 뇌출혈을 동반한 인공판막 심내막염 국내 첫 증례가 확인되었기에 보고한다. 인공 대동맥판막 수술력이 있는 65세 남자 환자가 발열을 주소로 본원 감염내과 외래에 내원하였다. 발열 후 30일째 시행된 혈액배양검사 중 한쌍에서 R. mucilaginosa 가 동정되었다. 뇌 자기공명영상검사에서 양쪽 대뇌반구, 피질과 수질의 접합부, 소뇌에서 패혈성색전증을 시사하는 미세출혈 소견이 확인되었다. 뇌출혈을 동반한 감염성 심내막염에서 Rothia 종은 원인균으로 고려되어야 한다.
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