ABDOMINAL WALL THICKNESS AFFECTS LIVER STIFFNESS MEASUREMENTS BY 2-D SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH CHRONIC LIVER DISEASE
- Authors
- Cho, Young Seo; Lim, Sanghyeok; Kim, Yongsoo; Kim, Tae Yeob; Jeong, Woo Kyoung; Sohn, Joo Hyun
- Issue Date
- Oct-2019
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Elasticity imaging techniques; Liver; Fibrosis; Abdominal wall
- Citation
- ULTRASOUND IN MEDICINE AND BIOLOGY, v.45, no.10, pp.2697 - 2703
- Indexed
- SCIE
SCOPUS
- Journal Title
- ULTRASOUND IN MEDICINE AND BIOLOGY
- Volume
- 45
- Number
- 10
- Start Page
- 2697
- End Page
- 2703
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/12511
- DOI
- 10.1016/j.ultrasmedbio.2019.06.415
- ISSN
- 0301-5629
- Abstract
- This study was conducted to define the effect of abdominal wall thickness (AWT) and its composition on the level of confidence in liver stiffness (LS) measurements obtained with 2-D shear wave elastography (2-D-SWE) in patients with chronic liver disease. In this retrospective study, a total of 1291 patients who underwent LS measurement by 2-D-SWE were enrolled. The abdominal wall was divided into three layers: layer 1 extended from the skin to the subcutaneous fat layer; layer 2 was the muscle layer; and layer 3 extended from the peritoneum to the liver capsule (including the omental fat layer, if present). We regarded the sums of layers 1-3 and layers 1 and 3 as the AWT and non-muscular layer thickness (NMT). Age/sex/body mass index-adjusted multivariate logistic regression analysis was performed to identify factors influencing the level of confidence of LS measurements. Three hundred eighty-six patients (29.9%) were classified in the unreliable LS group (standard deviation/median LS > 0.1). The fourth quartile of AWT and third and fourth quartiles of NMT/AWT were significantly associated with unreliable LS values (odds ratios = 2.103, 1.753 and 1.695, respectively). In conclusion, high AWT and NMT/AWT ratios reduce the confidence in LS measurements obtained with 2-D-SWE.
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