Validation of the Korean Quick Dementia Rating System (K-QDRS)
- Authors
- Ryu, Hui Jin; Moon, Yeonsil; Kim, Minyoung; Kim, Hee-Jin; Galvin, James E.; Han, Seol-Heui
- Issue Date
- Dec-2021
- Publisher
- IOS PRESS
- Keywords
- Activities of daily living; clinical dementia rating; cognition; dementia; neurocognitive disorders; screening
- Citation
- JOURNAL OF ALZHEIMERS DISEASE, v.84, no.4, pp.1645 - 1656
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF ALZHEIMERS DISEASE
- Volume
- 84
- Number
- 4
- Start Page
- 1645
- End Page
- 1656
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/138595
- DOI
- 10.3233/JAD-210584
- ISSN
- 1387-2877
- Abstract
- Background: The Quick Dementia Rating System (QDRS) is a brief and rapid dementia staging tool that does not require a trained rater. Objective: The purpose of this study is to demonstrate the validity, reliability, and diagnostic usefulness of the Korean version of the QDRS (K-QDRS). Methods: We collected a total of 411 subject-informant dyads including cognitively unimpaired (CU, n = 22), mild cognitive impairment (MCI, n = 198), and dementia (n = 191). The Clinical Dementia Rating (CDR) scale, Korean version of the Mini-Mental State Examination (K-MMSE), Korean version of instrumental activity of daily living (K-IADL), Short Form of the Geriatric Depression Scale, Caregiver-Administered Neuropsychiatric Inventory (CGA-NPI), and detailed neuropsychological tests were administered as gold standards of dementia staging, cognition, function, mood, and behavior. Results: Internal consistency of the K-QDRS was excellent with Cronbach's alpha of 0.933. Concurrent validity was also satisfactory, with the K-QDRS correlating highly with the CDR Sum of Boxes (Pearson's r = 0.791), K-MMSE (Pearson's r = -0.518), K-IADL (Pearson's r = 0.727), and CGA-NPI (Pearson's r = 0.700). The K-QDRS was highly correlated with the global CDR, K-IADL, and CGA-NPI. We suggested two types of comparisons (for initial diagnosis and for follow-up evaluation). The cutoff scores for follow-up were 1.0 for MCI, 3.5 for very mild dementia, 6.5 for mild dementia, and 11.0 for moderate dementia. Conclusion: The K-QDRS is a valid and reliable dementia rating questionnaire and can be used, briefly and rapidly, in various settings like clinical practices, longitudinal cohort studies, and community primary care.
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