COVID-19 Vaccine-Induced Multisystem Inflammatory Syndrome With Polyserositis Detected by FDG PET/CT
- Authors
- Lee, Soo Jin; Park, Dong Won; Sohn, Jang Won; Yoon, Ho Joo; Kim, Sang-Heon
- Issue Date
- May-2022
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- COVID-19; FDG PET; multisystem inflammatory syndrome; serositis; vaccine
- Citation
- CLINICAL NUCLEAR MEDICINE, v.47, no.5, pp.E397 - E398
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL NUCLEAR MEDICINE
- Volume
- 47
- Number
- 5
- Start Page
- E397
- End Page
- E398
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/138667
- DOI
- 10.1097/RLU.0000000000004094
- ISSN
- 0363-9762
- Abstract
- Of the various adverse reactions to COVID-19 vaccines, fever is a common systemic symptom that often resolves spontaneously without treatment. However, rare vaccine-induced conditions that present with fever and systemic inflammation have been reported. In this case, a 65-year-old man with BNT162b2 mRNA COVID-19 vaccination underwent F-18-FDG PET/CT to evaluate prolonged fever and elevated serum C-reactive protein. PET/CT showed hypermetabolic infiltration in the pericardium and peritoneum suggesting immune-mediated pericarditis and peritonitis. After administration of high-dose corticosteroids, the patient's symptom resolved. This case suggests that multisystem inflammatory syndrome and polyserositis can be induced by the COVID-19 vaccine.
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