감초 추출물 함유 키토산 나노캡슐의 특성 및 항산화 활성open accessCharacteristics of Glycyrrhiza uralensis extract-loaded chitosan nanocapsules and their antioxidant activity
- Other Titles
- Characteristics of Glycyrrhiza uralensis extract-loaded chitosan nanocapsules and their antioxidant activity
- Authors
- Kim, Min Jung; Lee, Ji-Soo; Lee, Hyeon Gyu
- Issue Date
- Aug-2021
- Publisher
- 한국식품과학회
- Keywords
- Glycyrrhiza uralensis; extraction; nanocapsule; antioxidant activity; oxidative stability
- Citation
- 한국식품과학회지, v.53, no.4, pp.479 - 485
- Indexed
- SCOPUS
KCI
- Journal Title
- 한국식품과학회지
- Volume
- 53
- Number
- 4
- Start Page
- 479
- End Page
- 485
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/141308
- DOI
- 10.9721/KJFST.2021.53.4.479
- ISSN
- 0367-6293
- Abstract
- To improve the oxidative stability of Glycyrrhiza uralensis extract (GU), GU extraction conditions were optimized for maximal antioxidant activity, and GU-loaded nanocapsules were prepared by chitosan ionic gelation. The optimized ethanol concentration and extraction time were 83.0% and 32.6 min, respectively, using response surface methodology. The particle size of the GU-loaded nanocapsules ranged from 280 to 370 nm. A GU extract of 0.8 mg/mL and chitosan concentration of 2.0 mg/mL were selected as the optimal conditions for entrapment and loading efficiency. Both free GU and GU-loaded chitosan nanocapsules exhibited concentration-dependent antioxidant activity. However, the antioxidant protection factor of GU was effectively maintained when it was entrapped within the chitosan nanocapsules. In conclusion, chitosan nanoencapsulation is a potentially valuable technique for improving the oxidative stability of GU.
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