Transition-metal-catalyzed ortho-selective C-H functionalization reactions of free phenols
- Authors
- Youn, So Won; Cho, Cheon-Gyu
- Issue Date
- Jun-2021
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- ORGANIC & BIOMOLECULAR CHEMISTRY, v.19, no.23, pp.5028 - 5047
- Indexed
- SCIE
SCOPUS
- Journal Title
- ORGANIC & BIOMOLECULAR CHEMISTRY
- Volume
- 19
- Number
- 23
- Start Page
- 5028
- End Page
- 5047
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/141829
- DOI
- 10.1039/d1ob00506e
- ISSN
- 1477-0520
- Abstract
- Phenols are important readily available chemical feedstocks and versatile synthetic building blocks for diverse synthetic transformations. Their motifs are prevalent in a diverse array of natural products, pharmaceuticals, functional materials, and privileged chiral ligands. Consequently, the development of facile and direct site-selective C-H bond functionalization of free phenols is of great importance and considerable interest to both industry and academic research. Over the past decades, transition-metal-catalyzed C-H bond functionalization has become as a powerful synthetic tool in organic synthesis. In this review, we provide a brief overview of recent progress in the transition-metal-catalyzed direct ortho-selective C-H functionalization of free phenols.
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